Poop Pill’s Surprise Failure Shows That the Microbiome is Still a Mystery
The original faecal transplant work was done in Glasgow and got written up here:
Faecal transplant for recurrent Clostridium difficile-associated diarrhoea: a UK case series.
What really stuck in my memory was his comment was that, as they removed the NG tube, the patient cured. Many of these these folks hadn't left the house, often never left the loo, for years before referral. Their next bowel movement was going to be normal.
With a success rate as high as documented there has never been a double blind placebo controlled trial. I rather like that.
So I can imagine him watching the development (as I did) of the multiple probiotic capsule which was (or wasn't!) going to cure C. difficile gut-rot without all of the "ick-factor" of the trip to Gartnavel. Then quietly going in to work to cure some more people, assisted by a pooh sample.