tag:blogger.com,1999:blog-36840063.post2323375672731238676..comments2024-03-18T22:09:37.509+00:00Comments on Hyperlipid: From Skulachev to LUCAPeterhttp://www.blogger.com/profile/14527788116058656094noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-36840063.post-38909402963883846102017-04-20T05:08:22.213+00:002017-04-20T05:08:22.213+00:00Hi Jesrad,
Ouch. Skulachev does go on to talk abo...Hi Jesrad,<br /><br />Ouch. Skulachev does go on to talk about mammalian cells in the later section of the paper but I’ve not thought it through to the level of looking at aldosterone dyscrasias. I have to agree the recreational potential seems limited!!!!<br /><br />Samuel and karl, the body controls pH very, very tightly so I’m not one for alkaline diet ideas. Equally, unless you are on an ACE inhibitor (or have Addisons or jesrad’s problems!) you are going to off load excess K+ down the loo. Now, dealing with a deficiency of K+ is a much harder problem to sort out. But, on the whole organism basis, fat doesn’t use the insulin/K+ system in the same way as glucose…<br /><br />PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-29133004057996361952017-04-19T22:18:18.542+00:002017-04-19T22:18:18.542+00:00So our cells use sort of a potassium battery .
ht...So our cells use sort of a potassium battery .<br /><br />https://en.wikipedia.org/wiki/Potassium-ion_battery<br /><br />What happens after you run out of potassium? <br /><br />This appears to stabilize things when food appears and disappears - covers the feedback zero-crossing glitch. Without it - I think there would be ROS signaling noise.<br /><br /><br /><br /><br />,.,.<br /><br />I'm also remembering the some connection of potassium with sore muscles...karlhttps://www.blogger.com/profile/13490274388549702613noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-47469735616554960042017-04-19T19:16:45.317+00:002017-04-19T19:16:45.317+00:00Hi,
Would these proton pumping mechanisms have an...Hi,<br /><br />Would these proton pumping mechanisms have anything to say about the weird 'alkaline diet'?, or possibly eating foods that are very high in potassium like fruits. Avocado of course for keto :) <br /><br />Thank you, Samtwiceearthhttps://www.blogger.com/profile/06086467073050278102noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-62079702346825824432017-04-19T16:56:42.208+00:002017-04-19T16:56:42.208+00:00Thank you for this very clear exposé.
As someone ...Thank you for this very clear exposé.<br /><br />As someone who has a serious imbalance of Na+ and K+ (late-onset pseudohypoaldosteronism type 1) my body keeps me well aware of the carb intake and K+ levels dynamics... actuely so.<br /><br />Did you know resting too long at night after having had carbs at dinner can cause hyperkalemic paralysis the next morning ? It's a lot less fun than it sounds. Maybe having too much energy lying around and not any mean to do something useful with it is not a good thing, metabolically.<br /><br />In situations where the organism is depleted of Na+ and has an excess of K+, could the mechanism you describe for compensating the alkalization of the intracellular medium fail ? I know I always get metabolic acidosis after prolonged efforts, it could be developping in the intercellular level. Going alkaline inside, and acid outside, hmm...<br /><br />In my experience, it also causes the worst kind of headache one could ever have: astrocytic swelling. Do you think there is any chance this inner/outer pH imbalance could be made worse in glucose-dependant cells, specifically ? What could be the osmotic consequences ?Anonymousnoreply@blogger.com