tag:blogger.com,1999:blog-36840063.post4861445733489226274..comments2024-03-27T22:57:00.742+00:00Comments on Hyperlipid: Getting fat, staying fatPeterhttp://www.blogger.com/profile/14527788116058656094noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-36840063.post-52520098091633852772012-01-18T22:14:33.520+00:002012-01-18T22:14:33.520+00:00Peter, have you heard of the Chinese Restaurant ef...Peter, have you heard of the Chinese Restaurant effect that Dr. Bernstein describes in his book, The Diabetes Solution? He says that overeating through the mechanism of stretching the stomach and gut will stimulate insulin (and glucagon, adna bunch of other stuff as well). It's relevant for Type I diabetics as glucagon is released with huge amounts of eating, which can not balanced with insulin. Overeating is a stimulant for insulin release. What do you think?Unknownhttps://www.blogger.com/profile/05955418159473734203noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-15818092939985135112010-05-23T05:38:09.352+00:002010-05-23T05:38:09.352+00:00Hmmmm, well I picked your comment up a day too lat...Hmmmm, well I picked your comment up a day too late to suggest that something based on marscapone cheese, topped with 85% cocoa chocolate diluted with butter and cream over a base of ground nuts set in butter tends to taste better...... Add judicious glucose powder or a little honey to flavour, not too much.<br /><br />Of course I was just going to give him steak when he gets up tonight.... Oh, maybe I should make <a href="http://1.bp.blogspot.com/_xlflFL230eI/R9Uh7VEQQwI/AAAAAAAAADU/hWjnKedCRcg/s1600-h/Cheesecake.JPG" rel="nofollow">the cake</a>?????? Good idea.<br /><br /><br /><br /><br /><br /><br />PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-91187868311238484932010-05-20T21:56:37.686+00:002010-05-20T21:56:37.686+00:00This is all very interesting but leaves me no furt...This is all very interesting but leaves me no further in making your son's birthday cake. Sculpt something suitably geeky out of lard perhaps?blackberrythornhttps://www.blogger.com/profile/15455730177321870990noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-35295516292069437632008-04-15T19:31:00.000+00:002008-04-15T19:31:00.000+00:00thanks for the comments.Reading further ASP only r...thanks for the comments.<BR/><BR/>Reading further ASP only really acts in terms of fat storage. Fat mobilisation and oxidation seem much more limited by insulin. Maybe it is just at the extremes of intake that ASP becomes an issue.Chrishttps://www.blogger.com/profile/00223657383325055342noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-11377191109495421642008-04-13T08:45:00.000+00:002008-04-13T08:45:00.000+00:00And looking at the other end of the process, adipo...And looking at the other end of the process, adipose tissue breakdown, hormone sensitive lipase is not the only system available. HSL knockout mice do do lipolysis, just not very well.... I guess that's evolution for you!<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-24377427550864951322008-04-11T21:13:00.000+00:002008-04-11T21:13:00.000+00:00Hi Chris,Thanks for that, haven't chance tonight t...Hi Chris,<BR/><BR/>Thanks for that, haven't chance tonight to check the refs but it doesn't surprise me. Within a given macronutrient framework calories do seem to matter, you CAN gain weight LC if you eat enough fat. It can be quite difficult, but you can do it. Even kids on ketogenic diets grow, though perhaps not as well as those eating a little more carbs.<BR/><BR/>I'll have a read soon<BR/><BR/>Ta<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-87038617087327970612008-04-11T21:00:00.000+00:002008-04-11T21:00:00.000+00:00Peterwith respect to your PS on this post, have yo...Peter<BR/><BR/>with respect to your PS on this post, have you ever looked at the role of Acylation Stimulating Protein (ASP)?<BR/><BR/>There is an article here for example:<BR/><BR/>http://tinyurl.com/5bsmux<BR/><BR/>I came across this in reading something the other day where the author was saying that while fat will not give an insulin response, Insulin is not the only hormone to worry about with respect to storing fat. <BR/><BR/>ASP he said is activated by chlyomicrons in the blood without any increase in insulin and eating fat even in the complete absence of insulin will affect both fat sorage and breakdown.<BR/><BR/>Two papers he pointed to are at <BR/><BR/>http://tinyurl.com/6l9q2w<BR/><BR/>and<BR/><BR/>http://tinyurl.com/5p3uyw<BR/><BR/><BR/><BR/>Any thoughts?Chrishttps://www.blogger.com/profile/00223657383325055342noreply@blogger.com