tag:blogger.com,1999:blog-36840063.post2245333882884703031..comments2024-03-29T06:45:45.894+00:00Comments on Hyperlipid: Physiological insulin resistance: The wild type micePeterhttp://www.blogger.com/profile/14527788116058656094noreply@blogger.comBlogger38125tag:blogger.com,1999:blog-36840063.post-4425674480935325472013-09-18T13:18:13.372+00:002013-09-18T13:18:13.372+00:00I love this post! Saw a recent article about Ornis...I love this post! Saw a recent article about Ornish reversing aging with vegetarianism and yoga, and I just couldn't resist having a laugh by searching the blog for 'Ornish' =)skepticlehttps://www.blogger.com/profile/05122498598662433174noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-59842579230374467012011-03-19T10:19:06.534+00:002011-03-19T10:19:06.534+00:00Hi williebr,
Yes, and not really. I run my muscle...Hi williebr,<br /><br />Yes, and not really. I run my muscles on FFAs so I have no need for them to be insulin sensitive. I do not do physical culture and absolutely do not have the physique of Anthony Colpo. Nor would I would want it.<br /><br />I can catch waves in my kayak as well as my mates running on carbs. That's good enough for me.<br /><br />PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-25670146928279082052011-03-19T01:42:48.349+00:002011-03-19T01:42:48.349+00:00Peter,
In the last paragraph of this post, were y...Peter,<br /><br />In the last paragraph of this post, were you saying that on a very high fat diet your lean tissue becomes insulin resistant so free-up glucose for your brain?<br /><br />If so, is that very good for optimizing body comp? You would want your lean tissue/muscle to be insulin sensitive right?williebrhttps://www.blogger.com/profile/14181695034119925135noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-53552139513025297762008-10-30T16:38:00.000+00:002008-10-30T16:38:00.000+00:00Hi Peter. I find your blog very interesting but am...Hi Peter. I find your blog very interesting but am still on the fence on many issues. <BR/>We know that fructose above say about4-6g /day is bad. But what about FOS such as is found in artichokes asparagus, chicory, yacon etc. These are all traditional vegetables and wikipedia says (search inulin) that many traditional diets contain in excess of 20g / day of inulin? According to many sites, Duncan Crow's site on curing candida in particular, it is said the long chain FOS cannot be used by -ve bowel bacteria and 1 study on his site shows that feeding of 15g inulin/ day makes bifidobacteria predominant in the colon. Plus, it has been shown that FOS is a component of breast milk. What is your take on this? As I say I am undecided.Ed Clementshttps://www.blogger.com/profile/12196873364805657410noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-29386878247344709992008-09-25T09:10:00.000+00:002008-09-25T09:10:00.000+00:00A paper with interesting epidemology.Does Total ch...A paper with interesting epidemology.<BR/>Does Total cholesterol increases with<BR/>lack of vitamin-D?<BR/><BR/>Coronary risk factors in Northern India<BR/><BR/>American Heart Journal,vol 79, 181-187 (1970 )<BR/><BR/>Donald N. Wysham M.D Kuldip C. Kohli M.B., B.S.and Sandra Mulholland<BR/>Department of Medicine, Christian Medical College, Ludhiana, Punjab, India.<BR/><BR/>Received 19 May 1969. <BR/><BR/>Abstract<BR/><BR/>A study was made of 175 sedentary male lawyers and bank employees between 40 and 60 years of age in Punjab, previous termIndia,next term to observe the relationship of diet, body build, and directed daily exercise to serum cholesterol levels. Dietary analysis was made from interviews. The consumption of previous termsaturated fatnext term was found to be moderately high (30 per cent of calories), and of cholesterol low (mean 126 mg. per day). Of dietary factors, only cholesterol was positively correlated to a significant degree with serum cholesterol. The effect of dietary cholesterol was small, with 3 mg. per cent change in serum cholesterol per 100 mg. of change in dietary cholesterol. Relative body weight appeared to have more influence than dietary factors on serum cholesterol. Short periods of daily exercise had no significant effect on serum cholesterol levels. Dietary sugar was found to be negatively correlated with serum cholesterol.Gyanhttps://www.blogger.com/profile/09941686166886986037noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-36199658035052463262008-09-23T15:43:00.000+00:002008-09-23T15:43:00.000+00:00Peter,I wonder if you're familiar w/ Rob Faigins "...Peter,<BR/><BR/>I wonder if you're familiar w/ Rob Faigins " Natural Hormonal Enhancement " ?<BR/><BR/>He combines low card days w/ carbo load days- the advantage being in the carb loading an increase in T3, an increase in the anabolic effect of insulin and a reduction in sex-hormone-binding globulin. He also states that periodic carb loading can enhance testosterone production @ the testicular level.<BR/><BR/>Thankssverlynhttps://www.blogger.com/profile/15620479807134061867noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-44805939839151386412008-09-23T13:42:00.000+00:002008-09-23T13:42:00.000+00:00Hi Water,Yes, amines might well be important for t...Hi Water,<BR/><BR/>Yes, amines might well be important for those who's acne doesn't go on LC alone. My skin is good enough that going Failsafe is too much like hard work! Depends where you are starting from I guess...<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-52609182871147200082008-09-23T13:15:00.000+00:002008-09-23T13:15:00.000+00:00I think there can be a histamine reaction from dai...I think there can be a histamine reaction from dairy also. <BR/><BR/>I just found this study after a major flare-up. I'm not on Failsafe, but beginning to suspect I could benefit from fewer amines at the very least.<BR/><BR/>(PMID: 18007585)<BR/><BR/>J Invest Dermatol. 2008 May;128(5):1280-5. Epub 2007 Nov 15.<BR/> <BR/>Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes.waterhttps://www.blogger.com/profile/14164346917947511229noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-15210074913067967812008-09-22T15:32:00.000+00:002008-09-22T15:32:00.000+00:00Hi Mark,No, I don't feel the cold much, it was a b...Hi Mark,<BR/><BR/>No, I don't feel the cold much, it was a bit of a standing joke back when I lived on the East coast where the wind is lazy (goes through you, not round you!). Back on carbs I was surfing cold waves but tended to get very, very cold and take some time to thaw afterwards. Used to get exhausted too, with no "pull" in the arms to get out through the break after an hour or so. Things are easier and warmer on NEFA.<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-71937632168665902672008-09-21T20:40:00.000+00:002008-09-21T20:40:00.000+00:00Hi Gunther,No time to read the dairy links yet but...Hi Gunther,<BR/><BR/>No time to read the dairy links yet but on the list...<BR/><BR/>Re chocolate I rather like the idea that any appetite increase comes from the inhibition of the break down of endocanabinoids.<BR/><BR/>May not be the correct answer but I like it!<BR/><BR/>Re allergy to chocolate Marco, no, no problems from Squiggs on that front. More problems with impetigo which seems to be triggered by salicylates, blackberries and raspberries (his favourites) seem to be a trigger...<BR/><BR/>If you do have a genuine allergy problem you would have to think way beyond just the theobromine to the host of other compounds in a plant derived food... Chocolate contains amines and certainly histamine triggers sneezing. There might be more about this on Emma's blog and it's links to the failsafe diet about amine/salicylate sensitivity.<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-57124188211633795692008-09-21T20:22:00.000+00:002008-09-21T20:22:00.000+00:00Hi Lauren,Have to agree with Anna, Agave syrup mak...Hi Lauren,<BR/><BR/>Have to agree with Anna, Agave syrup makes HFCS look like a health food!<BR/><BR/>Despite possible minor exceptions fructose is fructose is fructose, and it's bad...<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-29428219343894915842008-09-21T18:41:00.000+00:002008-09-21T18:41:00.000+00:00Lauren,Good for you for inquiring about the latest...Lauren,<BR/><BR/>Good for you for inquiring about the latest darling of the "natural" sweetener world, agave syrup. I find the high % of fructose in agave syrup/nectar alarming and worthy of caution, to say the least (wikipedia says some brands are as much 92% fructose!). I like to think of agave syrup as an even faster method of producing human foie gras (fatty liver) than HFCS.. hee-hee.Annahttps://www.blogger.com/profile/17033443643442246531noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-9221272823980700342008-09-21T16:21:00.000+00:002008-09-21T16:21:00.000+00:00I have a question Peter. Since you have a scientif...I have a question Peter. Since you have a scientific background and can look at scientific studies with a trained eye, will you please see what you can find regarding agave nectar (Agave Tequilana/Azul Tequilana)? It seems to be the "it" sweetener right now in the U.S. with vegans and those seeking a low-glycemic "natural" alternative to white sugar and honey. What's your take on agave's physiological impact? What about the high concentration of fructose in agave, and its long term effects on the human body? I've found only one study on PubMed talking about it.<BR/><BR/>Thanks for any info!Laurenhttps://www.blogger.com/profile/12992918908739085132noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-56923202086821857672008-09-21T15:43:00.000+00:002008-09-21T15:43:00.000+00:00Dark chocolate (72% or 85%) makes my 2 y.o. daught...Dark chocolate (72% or 85%) makes my 2 y.o. daughter SNEEZE.<BR/>Very immediate reaction.<BR/> <BR/>Whenever she has a little piece of chocolate she sneezes. <BR/>Always. <BR/>Even with the purest type. <BR/><BR/>Higher the cocoa in the chocolate, more immediate and stronger the reaction.<BR/><BR/>I read about a lot of people suffering from this on the web. <BR/><BR/>Allergy to theobromine?<BR/>Sort of "photic sneeze reflex"?<BR/><BR/>Anyone else has this problem? <BR/><BR/>Has Squiggs ever had this reaction, Peter?marcohttps://www.blogger.com/profile/06947136650432633637noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-57123040287149358862008-09-20T00:41:00.000+00:002008-09-20T00:41:00.000+00:00Hunger from chocolate is probably just the carb co...Hunger from chocolate is probably just the carb content... plus, chocolate is tasty and that could stimulate feeding centers in the brain; there is a link between beta endorphin release and insulin release. <A HREF="http://books.google.com/books?id=r_XsYYsmF68C&pg=PA212&lpg=PA212&dq=chocolate+beta+endorphin&source=web&ots=2CGDeUrWIj&sig=xHdlI78MOxOktQAAXKF8d4o4EG8&hl=en&sa=X&oi=book_result&resnum=3&ct=result#PPA212,M1" REL="nofollow">Chocolate stimulates beta endorphin</A>. Coffee does as well, which is why people tend to feel calm and satisfied after a coffee (it's not the dopamine, it's the endorphin).<BR/><BR/>According to the link above, opioid-mediated feeding plays a big role in "emotional eating". Any eating that is done after stress: fasting, starving, or non-food stress produces a big opioid response to food, which in turn causes insulin release. <BR/><BR/>Predictable and monotonous feeding disengages the opioid system, which may have something to do with the theory that eating bland food regularly is slimming (e.g. shangrila diet). For a lot of women who hate protein and low carb foods, perhaps the diet works for this reason too (because the low carb food, for them, is monotonous and predictable whereas their usual feeding habits are to eat unpredictably and of very enjoyable food). I can't help but notice a lot of dieters have an innate fear of enjoyable flavorful food (e.g. splenda and chocolate) and I wonder if it is because their weight gain and eating is more mediated by the opioid induced insulin secretion?ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-26544450096628973082008-09-19T21:33:00.000+00:002008-09-19T21:33:00.000+00:00Hi guys.Excellent discussion you are having on dai...Hi guys.<BR/><BR/>Excellent discussion you are having on dairy.<BR/><BR/>I've found my ideal morning drink, quite low in caffeine: butter tea. Just make strong tea (I use organic Ayurverdic chai, which is 35 % black tea by weight), then add butter (I add maybe 4-5 tablespoons of cultured organic butter per half pint). Then blend or shake it until the butter stops separating. For added goodness, blend or shake it a lot to create a large layer of foam (I use a stick blender for this end). Delicious. They tend to drink a lot of it in Tibet. I guess you can add some (fermented) cream as well.<BR/><BR/>Praise the lard!<BR/>Emil.emil henryhttps://www.blogger.com/profile/18294259840297513383noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-51678461099942308302008-09-19T19:40:00.000+00:002008-09-19T19:40:00.000+00:00Yeah, Gunther. I have taken chocolate in and out ...Yeah, Gunther. <BR/><BR/>I have taken chocolate in and out of the diet, mainly for economic reasons. Used to buy this Polish Wawel chocolate for 1.50 Canadian for 90% cocoa, but they lowered the cocoa butter concentration and upped the cocoa powder, so more protein, less fat. So not economic reason, but fat content. Now I have moved and am purchasing Lindt chocolates at an outlet mall 10 for 12.00 USD, which the whole family is in joy over.<BR/><BR/>Anyway, yeah, chocolate does make me hungrier. Or maybe I am hungrier and therefore eat chocolate because I have not enough to eat. Not sure on the cause there lol. <BR/><BR/>BTW, I am weighing in at 148 pounds or so, and can hit up to 155 on a high fat diet and not feel sluggish. I am very low body-fat %-wise, and have a small frame. I think the reason Peter may not put on much weight on his calories is lack of protein to put on muscle mass? Obviously no proof for this, but suspect instead calories are going into metabolism. I eat virtually the same as Peter, except I'm eating less calories than he does. My carb content is same, if not lower, and my protein content is higher maybe by double is the major difference between my diet and his. <BR/><BR/>Peter, you get cold much?<BR/><BR/>Think when you go surfing, it's cold as all hell and you can hack it. I don't handle cold well. I wonder if you have an amped metabolism from the calories that results in overheating, and that's where your calories are going to. <BR/><BR/>Mark.Markhttps://www.blogger.com/profile/16922415954626790524noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-92175301624259847012008-09-19T19:24:00.000+00:002008-09-19T19:24:00.000+00:00Peter, Here's an update on the Fat Challenge: it s...Peter, <BR/><BR/>Here's an update on the Fat Challenge: it seems obvious, but there is a limit to how much you can eat of it without feeling totally over-full and disgusting. I tried to eat loads more fat calories after reaching 65kg, and failed because it made me into a lifeless slug. The exercise seemed pointless, since I was never going to live like that anyway, so I gave it up. <BR/><BR/>I can't really tell you the outcome. The problem is that you can't tell if you gained weight or not when you've got 3 times more food in your stomach. In any case, I didn't feel fatter and my clothes fit the same after ten days trying to gain weight by upping fat.<BR/><BR/>Bruce made a comment in another blog entry of yours that has really proven to be true: taking chocolate out of my daily diet resulted in MUCH less hunger and I felt much fuller much longer after eating. Any reason why this could be? I also find coffee, even decaf, makes me hungry afterwards too. <BR/><BR/>Has anyone else tried taking the 85% chocolate out to see how they feel?<BR/><BR/>Ggunther gathererhttps://www.blogger.com/profile/15361732213105267048noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-68865519748570875102008-09-18T14:47:00.000+00:002008-09-18T14:47:00.000+00:00At the optimal polish deli in chicago, they sell "...At the optimal polish deli in chicago, they sell "settled" goats milk. Fresh from the farm and fermented. Oh, so good. Makes me think that this is what yogurt used to be.mess talkerhttps://www.blogger.com/profile/10673067295817519593noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-61495636376867722072008-09-18T05:06:00.000+00:002008-09-18T05:06:00.000+00:00Hi Brad (and ItsTheWoo),Can't really comment as th...Hi Brad (and ItsTheWoo),<BR/><BR/>Can't really comment as this is the first I've heard of it. The whole subject of nutrition and metabolism is so huge you can only delve in to certain bits... My gut feeling is that I always drift back to whole foods I guess. But then my preferred physique is one which would allow me to blend in to a well nourished HG society... But there again milk is designed to convert little calves to big calves so I can see why it might work for bodybuilding.<BR/><BR/>This comes back to ItsTheWoo's suggestion about insulin mimetic/release stimulants in milk, they're certainly there. And the body building gurus are well aware of the role of insulin as a muscle builder. <BR/><BR/>Before refrigeration and trains relatively few people would have access to fresh milk and humans do seem to have a long tradition of culturing it. Back when I could get "house cow" milk I used to just leave it a room temperature overnight and let it self culture. It was good.<BR/><BR/>Hi Sverlyn,<BR/><BR/>I'd heard Barry Groves had a new book on the way, didn't realise it was so close to publication!<BR/><BR/>PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-74859571470517854932008-09-17T23:30:00.000+00:002008-09-17T23:30:00.000+00:00New book listed @ Amazon:Trick And Treat - how 'he...New book listed @ Amazon:<BR/><BR/>Trick And Treat - how 'healthy eating' is making us ill (Paperback)<BR/>BY Barry Grives<BR/><BR/>Few people have 'old age' as a cause of death on their death certificate.Today, we die of cancer, heart attacks, strokes, osteoporosis, diabetes…And we accept these conditions as normal causes of death.They aren't - and neither is the ill-health, pain and discomfort that make our later years a misery.<BR/><BR/>In this controversial, evidence-based account of how and why the health-care establishment has got the concept of 'healthy eating' so wrong, Barry Groves shows us how to take charge of our own health and lives, in contravention of what the health-care industry would have us believe and do.<BR/><BR/>Contents<BR/>Part I: How 'Healthy Eating' Is Making Us Ill<BR/>1. Medical Corruption<BR/>2. What's Behind The Screen$?<BR/>3. How We Got To Where We Are<BR/>4. Learning From History<BR/>5. Fats: From Tonic to Toxic<BR/>6. The Seeds of Ill Health<BR/>7. Climb Off The Bran Wagon<BR/>8. Why 'Five Portions'?<BR/>9. The Phoney War On Salt<BR/>10. Soy, Fluoride and the Thyroid<BR/>11. Our Irrational Fear of Sunlight<BR/>12. Exercise Care<BR/>13. Homo Carnivorous<BR/>14. The Metabolic Syndrome And Glycaemic Index<BR/>15. Unhealthy Dogma Means Unhealthy Diet<BR/>16. So What Should We Eat?<BR/>17. Why Low Carb Diets Must Be High Fat, Not High Protein<BR/>18. You Are What Your Grandparents Ate<BR/>19. Prevention is Better<BR/><BR/>Part II: New Diet, New Diseases<BR/>20. ' Healthy Eating' is Fattening<BR/>21. The Diabetes Time Bomb<BR/>22. Diseases of the Heart and Blood Vessels<BR/>23. The Dangers of Low Blood Cholesterol<BR/>24. Cancer:Disease of Civilization<BR/>25. Gut Reaction<BR/>26. Deficiency Diseases<BR/>27. Diet and the Brain<BR/>28. Multiple Sclerosis<BR/>29. ' Healthy Eating' Shows<BR/>30. And Finally . . .<BR/><BR/><BR/>About the Author<BR/>Barry Groves, who lives with his wife, Monica, in the Oxfordshire Cotswolds, can rightfully claim to be Britain's leading exponent of the low-carb way of life as he has lived on, researched, lectured and written about it for well over 40 years.<BR/><BR/>He and Monica were overweight from 1957 to 1962, when he discovered the low-carb regime for weight loss. It worked; they haven't been overweight since.This started his questioning of conventional diets.As a consequence he took up full-time research into the relationship between diet and 'diseases of civilisation' such as obesity, diabetes, heart disease and cancer. As a result of his researches, he realised that the perceived wisdoms, both of low-calorie dieting for weight loss and 'healthy eating' for the control of heart disease, were seriously flawed.<BR/><BR/>Now an award winning international author with a doctorate in nutritional science, Barry has written both popular and more technical books which have been published in countries as far apart as Argentina and Russia, as well as all English-speaking countries. He currently divides his time between researching, lecturing and writing books about the management and prevention of obesity, diabetes and associated conditions.sverlynhttps://www.blogger.com/profile/15620479807134061867noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-66249419008804385122008-09-17T22:51:00.000+00:002008-09-17T22:51:00.000+00:00If unfermented cream brings acne as well as weight...If unfermented cream brings acne as well as weight / hunger problems, I would look to <I>growth hormones, insulin-stimulating proteins</I> which are naturally found in milk, and *especially* in factory-farmed milk. For me, acne is the #1 sign I am overdoing carbohydrates (have not had carb-related acne in months since I never go overboard with carbs anymore).<BR/><BR/>Fermenting probably destroys these proteins (casein?), thereby making the cream endocrinologically benign. Result? An end to acne, as well as inappropriate insulin release, but plenty of yummy cream to enjoy.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-23426754155667371222008-09-17T21:18:00.000+00:002008-09-17T21:18:00.000+00:00Peter/All,I wonder what your thoughts would be reg...Peter/All,<BR/><BR/>I wonder what your thoughts would be regarding Micellar Casein protein powders, available here in the U.S.A. for an "arm and a leg." Essentially, and as best as I can tell, Micellar Casein is protein powder derived from "undenatured" milk sources, that is, milk not exposed to heat, ultraviolet light, chemicals, etc.<BR/><BR/>At least one observer has suggested that a well-known protein powder peddler used Micellar Casein as sort of a magic ingredient early on to establish the efficacy of its protein, then owing to its high cost, after the protein developed an extensive following, dropped it from their formula. Which one? MetRx.<BR/><BR/>I know the majority of folks on this site have less enthusiasm for the muscle-building qualities of diet and focus more on other nutritional aspects, but I wonder what any of your thoughts would be regarding Micellar Casein, presumably not pasteurized as that would imply heat treatment, and its viability as a protein source for a high fat diet.<BR/><BR/>Cheers! Brad R.Brad Reidhttps://www.blogger.com/profile/10275394962283072954noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-28853823935797171612008-09-17T12:28:00.000+00:002008-09-17T12:28:00.000+00:00This last one concludes that "proteolysis during f...This last one concludes that "proteolysis during fermentation may lead to the formation of novel peptides during gastrointestinal ingestion." <BR/><BR/>Fermentation breaks the 28 chain so it doesn't go through the gut wall and/or creates a new way to digest the milk amino acids??<BR/><BR/>Pass the yogurt.gunther gathererhttps://www.blogger.com/profile/15361732213105267048noreply@blogger.comtag:blogger.com,1999:blog-36840063.post-32635082800013407752008-09-17T12:24:00.000+00:002008-09-17T12:24:00.000+00:00Here's another one. Yes, I know it's a dairy indus...Here's another one. Yes, I know it's a dairy industry study, but the results, if there are any, don't seem to favour them one way or the other...<BR/><BR/>http://jds.fass.org/cgi/reprint/79/6/971gunther gathererhttps://www.blogger.com/profile/15361732213105267048noreply@blogger.com