Hyperlipid

You need to get calories from somewhere, should it be from carbohydrate or fat?

Tuesday, July 21, 2020

Protons (56) The miracle of fish oil (3)

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I think this one is too important to leave it where George Henderson posted it in comments: Of mice and men: Factors abrogating the antiob...
4 comments:
Tuesday, July 14, 2020

Protons (55) The miracle of fish oil (2)

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I have a feed to my email account which has worked out that I am interested in longevity studies and particularly the role of PUFA in the in...
28 comments:
Tuesday, July 07, 2020

Pesky PSCK9 inhibitors (2)

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Eric put various links in the comments to the first PSCK9 post leading, eventually, to this study: Sequence Variations in PCSK9, Low LDL, ...
12 comments:
Sunday, July 05, 2020

Protons (54) The miracle of fish oil

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This paper has absolutely nothing to do with obesity: Feeding into old age: long-term effects of dietary fatty acid supplementation on tis...
27 comments:
Thursday, July 02, 2020

Pesky PSCK9 inhibitors

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For a variety of reasons I'm rather ignoring the blog at the moment. But this is too good not to post, HT to Carlos Monteiro for the lin...
14 comments:
Wednesday, June 03, 2020

ARDS and Tucker Goodrich

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Tucker has been very, very busy over the last few weeks. Does Consumption of Omega-6 Seed Oils Worsen ARDS and COVID-19? You will ne...
17 comments:
Thursday, May 28, 2020

Blood "energy" content

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"One-liner" post. This is exciting (picked up on twitter from Mike Eades): Effects of dietary carbohydrate content on circulatin...
16 comments:
Wednesday, May 27, 2020

Fancy some serology? (3) In Japan

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I notice that the COVID-19 state of emergency has been lifted in the last remaining areas of Japan as of last Monday. I think they lost...
16 comments:
Thursday, May 21, 2020

Fancy some serology? (2)

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I thought I would just take a break from trying to simplify the Protons electron transport chain as regards ultra low fat diets and talk abo...
7 comments:
Saturday, May 16, 2020

Low fat vs low carb again (2)

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For your enjoyment I have simplified this graph from Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Productio...
32 comments:
Thursday, May 14, 2020

Low fat vs low carb again

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I guess everyone knows about this pre-print A plant-based, low-fat diet decreases ad libitum energy intake compared to an animal-based, ke...
22 comments:
Thursday, May 07, 2020

Fancy some serology?

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Just a one liner-ish type post. I had the privilege of listening-in to one of the weekly Royal College of Pathologist webinars on the SARS...
46 comments:
Monday, May 04, 2020

Surwit diet and derivatives (3) 5LJ5 vs D12330: Chow vs Surwit

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TLDR: A "healthy", complex carbohydrate, low glycaemic index diet appears to markedly shorten the median lifespan of mice when com...
24 comments:
Saturday, May 02, 2020

Surwit diet and derivatives (2) It's the insulin

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EDIT Please ignore any ref to sucrose as the Surwit type diet used here contained none. My apologies. END  EDIT. I've been spending some...
5 comments:
Thursday, April 30, 2020

Surwit diet and derivatives

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As a counterbalance to the papers documenting the obesogenic effect of PUFA containing diets I'd like to have a brief aside about the Su...
8 comments:
Tuesday, April 28, 2020

The miracle of safflower oil (4) Soybean oil is just as good

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I picked this paper up from George Henderson via twitter Effects of dietary fat on gut microbiota and faecal metabolites, and their relati...
15 comments:
Monday, April 27, 2020

The miracle of safflower oil (3)

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TLDR: PUFA in a mixed diet are obesogenic. PUFA under hypoinsulinaemic conditions are not. I doubt they get a free pass long term. There...
13 comments:
Wednesday, April 22, 2020

The miracle of safflower oil (2)

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Just a brief mention of this one: Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of...
7 comments:

The miracle of safflower oil

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TLDR: Increasing insulin sensitivity makes you fat. This study is a bit of a mess because there are no control groups. People either got t...
25 comments:
Monday, April 20, 2020

Double Bond Index and longevity in humans

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Preamble: I've had this post written for some time (there are a fair few in this category) but this tweet from the World Health Organisa...
18 comments:
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Peter
I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.
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