Hyperlipid

Preamble/caveat. You have to be careful with Astrup's work over the years. When you get in to the fine print some of his control groups ...

I've got these three, apparently independent, origins for the concept that insulin resistance is an evolutionary conserved mechanism, es...

Let's go back to butter vs PUFA as in the last post . I'm going to use reductio ad absurdum to try make it absolutely clear why a fa...

I am firmly convinced that linoleic acid induces the rapid onset of insulin resistance in humans. This is beautifully illustrated by this pa...

I was searching my hard drive for another paper when I came across this one: Substituting dietary saturated fat with polyunsaturated fat cha...

I wrote this post several months ago but never got round to publishing it. Here we go. I don't like this paper. Targeting LDL improves i...

This paper Insulin resistance is a cellular antioxidant defense mechanism presents one of the most fundamental concepts necessary to underst...

Here's the next paper: Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis I would suggest that the ...

Hyperinsulinaemia, while being unable to suppress basal lipolysis, is still able to facilitate uptake and storage of fatty acids within adip...

Preamble. Direct quotes from Carpentier : "Ra glycerol , a marker of total AT lipolytic rate ..." "Plasma glycerol appearance...

I've been wanting to write about this paper for some time. But it annoys me. A lot. Increased postprandial nonesterified fatty acid effl...

It occurred to me while finishing the Carpentier post that it is a beautiful model of metabolic syndrome. My definition of insulin resistanc...

I went to Edinburgh for a CPD meeting and skipped social media for four days. I've come back ready to leave it alone for a while longer ...