Hyperlipid

You need to get calories from somewhere, should it be from carbohydrate or fat?

Monday, July 28, 2025

Protons (82) Size matters

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Here's the next paper: Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis I would suggest that the ...
4 comments:
Thursday, July 17, 2025

Protons (81) Crown like structures

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Hyperinsulinaemia, while being unable to suppress basal lipolysis, is still able to facilitate uptake and storage of fatty acids within adip...
11 comments:
Wednesday, July 16, 2025

Protons (80) The Carpentier Paradox (Carpentier III)

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Preamble. Direct quotes from Carpentier : "Ra glycerol , a marker of total AT lipolytic rate ..." "Plasma glycerol appearance...
5 comments:
Monday, July 07, 2025

Protons (80) Carpentier II

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I've been wanting to write about this paper for some time. But it annoys me. A lot. Increased postprandial nonesterified fatty acid effl...
7 comments:
Saturday, July 05, 2025

Protons (79) Define insulin resistance

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It occurred to me while finishing the Carpentier post that it is a beautiful model of metabolic syndrome. My definition of insulin resistanc...
Thursday, July 03, 2025

Protons (78) Carpentier

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I went to Edinburgh for a CPD meeting and skipped social media for four days. I've come back ready to leave it alone for a while longer ...
2 comments:
Tuesday, February 18, 2025

Scopinaro and biliarypancreatic diversion

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The late Nicola Scopinaro was an interesting chap. I came across him while reading about the use of the biliarypancreatic diversion (BPD) op...
8 comments:
Saturday, February 08, 2025

Synchronicity and the origins of Protons (2)

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This is the paper which Amber mentioned in her podcast conversation , primarily in the context that low carbohydrate, high fat diets marked...
3 comments:
Monday, February 03, 2025

Synchronicity and the origins of Protons

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Amber O'Hearn has a podcast conversation up on Spotify with  LowCarbLogic here . Very early on in the discussion she mentions this parti...
15 comments:
Thursday, January 23, 2025

Satiety (06) The MCAT mice

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Tucker emailed me this paper while I was writing the  last post : In adipose tissue, increased mitochondrial emission of reactive oxygen spe...
2 comments:
Saturday, January 11, 2025

Satiety (05) Threonine/alanine and the fasting insulin resistance

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Shulman had a "That's interesting" moment in his  2016 paper  which unfortunately got filed under "everything else was as...
2 comments:
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Peter
I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.
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