Hyperlipid

You need to get calories from somewhere, should it be from carbohydrate or fat?

Thursday, February 16, 2012

NASH on a ketogenic diet

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Just a brief post on the development of NASH in long term ketogenic fed mice because I've been side tracked by some other papers: Starva...
54 comments:
Friday, February 03, 2012

FIRKO-ise

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Question: How do you convert a C57BL/6 mouse in to a FIRKO mouse? Answer: Easily. First, break your mouse. Both the grey squares and white t...
68 comments:
Wednesday, February 01, 2012

The books

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As we all know, there is a spate of new books out at the moment. I see that Dr Briffa is on Jimmy Moore's LLVDLC. John sent me a copy of...
7 comments:
Monday, January 23, 2012

FIRKO mice

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Okay. I have an apology to make. I'm not sure there will be an MCQ test on the FIRKO mouse to parallel that on the LIRKO mouse . At this...
78 comments:
Tuesday, January 17, 2012

Used brain for sale: One careful owner, only slightly broken

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Let's start with the old Stranglers track, "No More Heros", take an ice pick to a rat's brain and make its ears burn. OK, ...
118 comments:
Saturday, January 07, 2012

More of the 17% solution

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There are various little one-liner papers which I've tripped over in the last few weeks which are probably worth a post although are not...
50 comments:
Saturday, December 31, 2011

Cake and cream

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Serving suggestions for soured cream not really needed... The ginger cake (in the last post) isn't really low carb but it helps keep the...
24 comments:
Monday, December 19, 2011

Update

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Danish butter is on offer in at least one UK supermarket, currently 10% less than economy butter. Surprise surprise. No better way to eat (g...
57 comments:
Monday, November 21, 2011

Adipotide and the Bad Fat

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Just a brief respite from mitochondria: Adipotide is a drug which targets the blood vessels supplying adipose tissue. It causes impressive f...
97 comments:
Thursday, November 10, 2011

LIRKO mice (3) The MCQ

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**************EDIT - This is serious************** It has been pointed out that this post is a deliberate intention to mislead. I would like...
65 comments:
Friday, November 04, 2011

Metabolic flexibility and the identical twins

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This post is highly speculative. It doesn't have any answers. Here is a nice quote to begin with: "If you want to retain your sanit...
20 comments:
Wednesday, October 12, 2011

The Adipostat balloon

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Right, back to links from Mary Rogge's paper on the role of impaired mitochondrial fatty acid oxidation in the obese. She links to Rude...
130 comments:
Thursday, October 06, 2011

Adipocyte insulin resistance

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It was in late 2007 that I first blogged about the concept of adipocyte insulin resistance and of course it is back in my mind while I work...
96 comments:
Tuesday, October 04, 2011

Denmark purchased using Flora profits?

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Ali prompted me to put up this link and I see Barry Groves has something up about it too. I think it was Iain Banks who wrote about corpora...
37 comments:
Saturday, October 01, 2011

HOW MANY bananas a day?

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Our daughter eats everything. Her ultimate favourite food so far is a purée of pig heart casseroled in red wine. We tried her on a banana, h...
24 comments:
Friday, September 30, 2011

Insulin resistant and slim. How slim?

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This Figure 4 from the paper by Shulman's group on mitchondrial dysfunction in the offspring of T2DM parents, the one the EMs came from...
15 comments:
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Peter
I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.
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