Hyperlipid

You need to get calories from somewhere, should it be from carbohydrate or fat?

Monday, May 23, 2016

The degradation of mitochondrial research

Does everyone remember this? Most especially this bit: Control is using pyruvate at 5 mmol/...

Will fasting destroy your mitochondria? (No).

I started with this paper: Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Huma...

Sunday, May 15, 2016

Fruit Flies and NDI1

The Protons thread originated when I asked myself: What is the difference between fat oxidation and glucose oxidation? This rapidly led to t...

Friday, May 13, 2016

Uncoupling in a can?

In response the suggestion from E-S, at top of comments to the last post, that caloric output should be measured using a calorimeter: Dire...

Wednesday, May 11, 2016

Uncoupling and weight loss

I've spent the last three posts making the point that fatty acid oxidation (supplemented by ketosis) increases the amount of ATP (and en...

Monday, May 02, 2016

On Stephen Phinney and an RQ of 0.62

****Edit**** There is an update on this post here ****End edit**** Now, oxidising long chain saturated fat gives you an RQ of 0.69. Lowe...

Friday, April 29, 2016

Endurance and oxygen flux during fatty acid oxidation

I was browsing Pubmed looking for other things when I came across this ancient publication by Stephen Phinney, from back in 1980. Those were...

Tuesday, April 26, 2016

Dave Asprey and Dr Veech

Dave Asprey has a very interesting extended discussion with Dr Veech on his Bulletproof website, mostly about ketones but also about the his...

Sunday, April 24, 2016

When is a ketogenic diet not a ketogenic diet?

I've listened to a few youtube/podcasts videos recently. Seyfried, Veech and D'Agostino appear to besettled in to what looks like a ...

Would Franklin have taken a statin if they had been available in the 1800s?

The Franklin expedition of 129 men perished in the Arctic, primarily of scurvy and related illnesses, in its entirety. I've been reading...

Glucosamine and aged mice

It would appear that glucosamine, the arthritis neutraceutical, promotes longevity. D-Glucosamine supplementation extends life span of nem...

Alcohol and fructose are the same to your liver

From Liz Miller via Facebook. Alcoholic Liver Disease: Update on the Role of Dietary Fat "The protective effects of dietary satura...

Friday, April 22, 2016

Dairy and diabetes

Mozaffarian has published this nice observational correlation between three markers of dairy consumption and subsequent onset of diabetes ov...

Tuesday, March 29, 2016

Stearate, butter and leptin receptors: Speculation!

I suppose the first thing I have to say is that the Tatter Paper of the last blog entry is not science in the form that any scientist migh...

Monday, March 21, 2016

Boiled mashed potatoes for miracle satiety?

The effects of potatoes and other carbohydrate side dishes consumed with meat on food intake, glycemia and satiety response in children . ...

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About Me

Peter: I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.

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