Hyperlipid

So this is the predicted structure of  the modern MrpA-like functional antiporter from N thermophilus, nt-Nha: cour...

A few years ago I mentioned this paper Homologous protein subunits from Escherichia coli NADH:quinone oxidoreductase can functionally repl...

Here is the basic Mrp antiporter structure as suggested in Structure of an Ancient Respiratory System Quite how many protons are exchang...

I notice the EU is considering approval for a plan to enforce removal of copyright infringing images form pretty well everywhere on T'in...

While I've been day dreaming about antiporters at the origin of life Tucker has been busy. I guess most people reading here would read T...

Just to summarise: The membrane bound hydrogenase (MBH) of Pyrococcus furiosus pushes a proton outwards through a proton permeable membrane ...

Sorry to go on about Yu et al's paper Structure of an Ancient Respiratory System but there's an awful lot in it. Here again is t...

I'm just following trails from the Mrp antiporter derived subunit of the membrane bound hydrogenase of Pyrococcus furiosus. The original...

Tom Naughton has a post up which pretty well sums up why I don't use twitter. It also encapsulates why I do respect those people who co...

OK, more doodles. More on Yu's paper . Back in 2015 I produced this diagram based around Nick Lane's ideas and labwork: Pleas...

Pyrococcus furiosus is an interesting organism. It has a penchant for living in environments at around 100degC. It looks like it has occupie...

I don't do twitter or facebook (If you are a metabolic person and have friend-requested me and I've ignored it please don't take...

Have a look at this: Limits of aerobic metabolism in cancer cells "To gain a better understanding of cell metabolism as a function ...

Using RQ to track whole body substrate oxidation is pretty straight forward. An RQ of 1.0 means glucose oxidation and of 0.69 indicates fat ...

You don't usually learn much from statements which you, personally, consider likely to be correct. Annoying statements are far more prod...

TLDR: Macavity, Macavity, there's no one like Macavity, He's broken every human law, he breaks the law of gravity. His power...

How does cell surface oxygen consumption happen? Here is the main reaction overall (it's probably not that simple!): 4e - + 4 H + + ...

Back in the comments thread to the More on insulin and the glycerophosphate shuttle post there has been some discussion as to whether Warbu...

It is perfectly possible to run a sophisticated metabolism using the energy available from an hydrogen rich geochemical proton gradient of t...

Tucker and Mike both gave me the heads-up on this paper recently. Linoleic acid causes greater weight gain than saturated fat without hypo...