Hyperlipid

You need to get calories from somewhere, should it be from carbohydrate or fat?

Wednesday, April 09, 2014

Dr Doug Wallace on mitochondria

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This link came to me from Bill Lagakos via Facebook. It covers a lot of ground and is, unavoidably, a little superficial in places when th...
54 comments:
Thursday, March 06, 2014

Would you like soya oil poured over your methionine spiked casein?

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Having a great week off work with my daughter, mostly swimming and gardening, so that blogging is off the radar as I'm fairly much off l...
18 comments:
Sunday, February 16, 2014

Protons (35) TFAM-KO revisited

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Those adipose tissue TFAM knockout mice need a revisit . They have an engineered, adipose tissue specific, catastrophic injury to complex I...
11 comments:
Monday, February 03, 2014

Dr Ravnskov on statins for primary prevention of CVD

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This is more of a Facebook link than a blog post, but hats off to the BMJ as they have recently published some excellent articles in which n...
53 comments:
Friday, January 31, 2014

TV Pantomine or the Oxford study

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I don't ever watch television (we have no digital decoding box, the TV is for DVDs) and I can't waste the time to watch  this perfor...
70 comments:
Saturday, January 25, 2014

An aside on psychiatric links from Sid Dishes

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Sid has recently put these two excellent links up on her Facebook timeline. The Protons thread is slowly working its way towards probable ca...
45 comments:
Thursday, January 23, 2014

Macrobiosis, macrobiopathy?

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I hope we all remember Barnad's low fat vegan treatment for diabetes. This figure sums it up: By 74 weeks folks are n...
13 comments:
Tuesday, January 21, 2014

I like this

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From Phillip (Thanks): Impaired glucose tolerance in low-carbohydrate diet: maybe only a physiological state . Like, like, like, like, ...
16 comments:
Sunday, January 19, 2014

Acipimox and insulin action

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I just wanted to put up a brief mention of this paper on acipimox. Acipimox is an inhibitor of lipolysis. It's essentially useless as...
20 comments:
Thursday, January 16, 2014

Protons (34) Rotenone

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So far I've been thinking about insulin resistance as a normal physiological process for regulating the energy input in to each cell, on...
23 comments:
Sunday, December 29, 2013

Protons (33) The mtG3Pdh knockout mice

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These mice keep asking me more questions that I'm comfortable with so the post is down subject to further thinking! Time for a Christ...
8 comments:
Tuesday, December 24, 2013

Protons (32) Post obese insulin induced thermogenesis

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Post-obese people are probably rarer than pre-obese people but at least they can be quite conclusively identified. The main problem with mos...
13 comments:
Saturday, December 21, 2013

Protons (31) insulin induced thermogenesis in the Pima

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I thought I might just put this snippet up as it's been lying around ready to go for some time. I've tried to tidy up some of the wo...
4 comments:
Wednesday, November 27, 2013

Protons (30) Uncoupling and metabolic rate in insulin resistance

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I wanted to look at insulin resistance, uncoupling and metabolic rate. If we just review the effect of an intravenous bolus of palmitic acid...
25 comments:
Sunday, November 24, 2013

Death by dogma

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It's amazing what you can find on the internet when you click on a link. I stumbled over this recently: Premature aging in mice activa...
21 comments:
Thursday, November 14, 2013

Ketoacidotic death in lactation!

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Laura forwarded me the link to this epic study: A gestational ketogenic diet alters maternal metabolic status as well as offspring physiol...
43 comments:
Tuesday, November 12, 2013

Protons (29) Uncoupling with fatty acids

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Trying to work out exactly what is happening in a given functional component of the inner mitochondrial membrane is not the most simple of u...
6 comments:
Tuesday, October 01, 2013

Polycystic Kidney Disease and mTOR

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I think I'm pretty well out of blogging time for the next month or so, so the post looking at fatty acids, uncoupling and insulin resist...
38 comments:
Saturday, September 21, 2013

Electron Transport Chain image

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Just off to bed. Wow, do I have wild Saturday nights! Had to share this lovely pic. One of the better representations of the ETC I've ev...
36 comments:

Wooo and the snps

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There seems to be quite a bit of interest going on in the LC Hardcore at the moment and I'm sat here, under my stone, looking at UCPs as...
31 comments:
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About Me

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Peter
I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.
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