Hyperlipid

You need to get calories from somewhere, should it be from carbohydrate or fat?

Monday, May 28, 2018

Speculation on the effect of subcutaneous adipocytes implanted in to the mesentery of mice

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Taking a piece of subcutaneous fat from a sacrificed mouse and implanting in to the mesentery of a recipient mouse causes weight loss in the...
6 comments:
Sunday, May 20, 2018

Guddling in the dark for a respiratory quotient (2)

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OK. I've been bugged by the RQ values which come out of CLAMS equipment. For months. Multiple papers have values that don't make sen...
12 comments:
Saturday, May 12, 2018

Nighttime Eaters have an elevated RQ on a given macro ratio diet. They're getting fat

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I picked up this paper via Face-ache so cannot recall to whom I should credit for the find. Sorry. The post is also highly speculative. Hi...
21 comments:
Friday, April 13, 2018

AHA approved egg!

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One of the full size chickens miss-fired yesterday and produced this minute egg: I was pretty sure this would be an AHA ...
19 comments:
Monday, April 09, 2018

Pasta for weight loss

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This paper hit T'internet recently and has been cited all over the place: Effect of pasta in the context of low-glycaemic index dietar...
13 comments:
Wednesday, March 21, 2018

Guddling in the dark for a respiratory quotient

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Here's a paradox: How can two groups of mice, on exactly the same chow, have different 24h averaged RQs, p less than 0.05? ...
17 comments:
Sunday, March 18, 2018

Eating lots of meat and nothing much else

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Wooo has posted a couple of times about Dr Shawn Baker who eats an all meat, very high protein diet, maybe over 400g/d protein intake....
61 comments:
Friday, March 16, 2018

On phosphorylating AKT in GHrKO Laron mice

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OK. I started this whole adipocyte thread because I was interested in the longevity effect in the GHrKO mouse, the Laron mouse. These posts ...
6 comments:
Sunday, March 11, 2018

On phosphorylating AKT: the penultimate half post

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I'm going to use some of Konrad's data to try and understand Kahn's data and the see if it will extrapolate to growth hormone re...
Thursday, March 08, 2018

On phosphorylating AKT: Interleukin-6 and a tale of two (or three) studies

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I've spent the last few days looking in great detail at this next paper. Mostly I'm interested in the effect of subcutaneous fat tra...
8 comments:
Sunday, March 04, 2018

On phosphorylation of AKT in real, live humans. They're just like mice!

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This first paper is very neat. They enrolled study subjects who were scheduled for an elective laparotomy and persuaded them to consent to a...
11 comments:
Saturday, March 03, 2018

On phosphorylating AKT in visceral adipocytes under starvation

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I was hoping to ignore the CR mice in the paper Differential response to caloric restriction of retroperitoneal, epididymal, and subcutane...
4 comments:
Friday, March 02, 2018

On phosphorylating AKT within visceral fat

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I've been thinking quite a lot about the difference between subcutaneous adipocytes and visceral adipocytes. The difference appears to b...
2 comments:
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Peter
I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.
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