An addendum to the mouse trans fat fibrosis paper: It's junk. Utter junk. Even the title is wrong. There are NO trans fats in the experiment, NONE what so ever!
The mice were fed on the Surwit Diet. Here's the pdf from Research Diets.
I thought medium chain trans fats were a bit of a strange animal....
So the mice are being fed on fully hydrogenated coconut oil, which has minimal PUFA to begin with and gets hydrogenated to fully saturated, mostly medium chain triglycerides. Plus non hydrogenated soya oil, which is mostly omega 6 PUFA and a little omega 3 PUFA.
The ONLY source of carbohydrate in the diet was sucrose and maltodextrin, which made up 25% of calories. To which they added sucrose in the drinking water, plus added fructose in the drinking water.
THERE ARE NO TRANS FATS IN THIS DIET.
Fructose, beyond human comprehension, with adequate soya oil, is enough to fibrose a mouse's liver. Not even Bill Clinton could eat this much fructose a day for life.
Who scrutineered this paper? Who wrote the title? How much money was wasted? What is happening in the world?
Ouch. Ouch. Ouch.
I'm trying to stop banging my head on the table but (Ouch)......