Jan Kwasniewski hates fasting. I'm not so sure it's as simple as this, there are some aspects which might be beneficial.
I started thinking about fasting when Dr Davis put up this post.
I'd just like to put this in to the perspective of glycoxidation. Let's look at glucose and lipid metabolism under a fast. There is no glucose uptake from the gut. The portal vein is no longer a glycation hot spot, the systemic circulation has only basal glucose too. Arterial endothelial cells are not undergoing hyperglycaemia induced apoptosis. This minimises the need for foam cell formation as there is essentially no damage needing repair.
Chylomicrons are not being produced at all, the liver is depleted of carbohydrate and so puts out a minimum of VLDLs. However many VLDLs and subsequent LDLs are actually produced, they will not be exposed to aggressive glycation conditions. If the liver does continue to produce significant levels of VLDL, they will be based either on fats synthesised from residual glycogen stores or free fatty acids derived from adipose tissue. That is, mostly saturated with some monounsaturated. So VLDLs will be deficient in PUFA and not prone to glycoxidation. PUFA supply will be limited to hepatic stores and whatever is present in adipose tissue, ie not a lot.
Bulk lipid for energy supply will be derived from adipose tissue lipolysis and be (a) mostly saturated fatty acids and (b) in free fatty acid form. You cannot glycate free fatty acids without direct free radical attack. No amino group on a FFA to form that horrible Schiff base.
From the perspective of someone who regards arteriosclerosis as a repair process gone horribly wrong, fasting has a lot to offer in the short term, with death in the long term. LC high saturated fat diets mimic fasting in several ways: There's never a lot of glucose in the portal vein and the chylomicrons based on saturated fats are pretty well glycoxidation proof. Fat gets stored as adipose tissue after each meal and is released as free fatty acids on demand. Metabolism mostly runs on free fatty acids. The big difference is that there is no (premature!) death if the diet is sustained for more than a few months!