Here we go
Peter
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You need to get calories from somewhere, should it be from carbohydrate or fat?
About Me
- Peter
- I am Petro Dobromylskyj, always known as Peter. I'm a vet, trained at the RVC, London University. I was fortunate enough to intercalate a BSc degree in physiology in to my veterinary degree. I was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow me to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. I stumbled on to nutrition completely by accident. Once you have been taught to think, it's hard to stop. I think about lots of things. These are some of them.
Organisation (or lack of it)!
The "labels" function on this blog has been used to function as an index and I've tended to group similar subjects together by using labels starting with identical text. If they're numbered within a similar label, start with (1). The archive is predominantly to show the posts I've put up in the last month, if people want to keep track of recent goings on. I might change it to the previous week if I ever get to time to put up enough posts in a week to justify it. That seems to be the best I can do within the limits of this blogging software!
Blog Archive
Labels
- !Kung Bushmen and mongongo nuts again (1)
- !Kung Bushmen and mongongo nuts yet again (1)
- A aargh BROKEN LINKS (1)
- A bit more on ketones and diabetic nephropathy (1)
- A brief aside in to statins and FH and all cause mortality (1)
- A brief discussion of ketosis (1)
- A defect of fat metabolism and a few thanks (1)
- A glimmer of light (1)
- A heads up (1)
- A little more on PCSK9 inhibitors (1)
- A load of crap in Gartnavel (1)
- A Peek at Paleo (1)
- A post not about Walter Kempner (1)
- A tale of two abstracts (1)
- A wander off in to dietary protein calories (1)
- ACCORD and musings on insulin (1)
- Acetoacetate and arterial oxygen tension (1)
- Acetone to oxaloacetate (1)
- Acipimox (2) and weight gain (1)
- Acipimox and insulin (1)
- Acipimox and insulin action (1)
- Adipose triglyceride lipase knockout mice (1)
- Adipotide and the Bad Fat (1)
- Adrian Ballinger on Everest (1)
- AGE RAGE and ALE (1): The AGE of LDL (1)
- AGE RAGE and ALE (2): The ALE of LDL (1)
- AGE RAGE and ALE (3): oxLDL (1)
- AGE RAGE and ALE (4): segregation (1)
- AGE RAGE and ALE (5): fasting (1)
- AGE RAGE and ALE (6): low fat (1)
- AGE RAGE and ALE (7): VLDL degradation (1)
- AGE RAGE and ALE (8): VLDL degradation and Krauss (1)
- AGE RAGE and ALE (9): VLDL degradation and Fish Oil (1)
- AGE RAGE and ALE posts (10): small dense Krauss (1)
- AGE RAGE and ALE posts (11): linoleic acid (1)
- AHA approved egg! (1)
- Alcohol and fructose are the same to your liver (1)
- Alcohol and weight loss (1)
- Alzheimer's (1)
- Alzheimers and ketones (1)
- Alzheimers and omega 6s (1)
- Alzheimers and Tau proteins (1) (1)
- Alzheimers and Tau proteins (2) (1)
- Amgen share price and PCSK9 inhibition with Repatha (1)
- Amgen share price and PCSK9 inhibition with Repatha (2) (1)
- an aside (1)
- An aside on psychiatric links from Sid Dishes (1)
- An embarrassment of cress (1)
- An Error (1)
- An exchange of half bricks (1)
- Anacetrapib and phytotoxins (1)
- Anger vs diet in Japan (1)
- Animal fat and cholesterol (1)
- ARDS and linoleic acid (1)
- ARDS and Tucker Goodrich (1)
- ARDS isoprostanes and isofurans (1)
- Are COVID-19 vaccines useful? (1)
- Are COVID-19 vaccines useful? (2) (1)
- Are COVID-19 vaccines useful? (3) (1)
- Are humans just multicellular yeasts? (1)
- Are ketone esters dangerous? (1)
- Are you lino-philic? (2) (1)
- Are you on clenbuterol? (3) (1)
- Are you trans-phobic? (1) (1)
- Arteriosclerosis (1) in 1957 (1)
- Arteriosclerosis (2) and sulphation factor (1)
- Arteriosclerosis (3) and von Willebrand Disease (1)
- Arteriosclerosis (4) GAG and sudden death (1)
- Arteriosclerosis (5) GAG and sudden death part two; the pictures (1)
- Arteriosclerosis (6) and Subbotin (1)
- Arteriosclerosis and saturated fat (1)
- Arteriosclerosis and the breeder rat (1)
- Arteriosclerosis images (2): Models (1)
- Athletic acid reflux (1)
- Atrial tachycardia and fibrillation (1)
- Axen and Axen (1) (1)
- Axen and Axen (2) (1)
- Axen and Axen (3) Hawks (1)
- Axen and Axen (4) Ketogenic insulin resistance. It's all over now... (1)
- Axen and Axen (5) The tradition continues (1)
- Back on line (2)
- Back to a semblance of normality: A couple of conversations (1)
- BAM15 and semaglutide are not insulin sensitising (1)
- Barja (1)
- Best ever statin study comment? (1)
- Best ever statin study? (1)
- Beta oxidation intermediates control ETC function (1)
- Blood "energy" content (1)
- Bob Michell on meta-analysis (1)
- Boiled mashed potatoes for miracle weight loss? (1)
- Boxes (1)
- Brain on a statin (1)
- Brain on chocolate (1)
- Brand insights (1)
- Brand on 4-HNE facilitated uncoupling (1)
- Breast cancer and starch (1)
- Breast cancer BRCA1 and metabolic syndrome (1)
- butter and leptin receptors: Speculation! (1)
- Butter gives you fatty liver! Again. (1)
- Butter insulin and Dr Davis (1)
- Butter vs peanut butter (1)
- Can linoleic acid keep you slim? (1)
- Cancer and ketones (1)
- Cardiac ischaemia and low carbohydrate diets (1)
- Casein and gluten and gastric pH (1)
- Casein vs gluten (1)
- Cat rawfeeding; scroll down the comments (1)
- Cell surface oxygen consumption (1) (1)
- Cell surface oxygen consumption (2) (1)
- Cell surface oxygen consumption (3) (1)
- Cell surface oxygen consumption (4) Influenza (1)
- Chicken fillets are not meat. If you're a cat. (1)
- Cholesterol (the HDL sort) kills? (1)
- Cholesterol and Carruthers (1)
- Cholesterol and cholestyramine (1)
- Cholesterol and heart attack survival (1)
- Cholesterol and innate immunity (1)
- Cholesterol and memory (1)
- Cholesterol and Son of J-LIT (1)
- Cholesterol and the J-LIT study (1)
- Cholesterol and the J-LIT update (1)
- Cholesterol fed rabbit (1)
- Cholesterol heart attacks and JUPITER (1)
- Cholesterol hypothesis in 2010 (1)
- Cholesterol hypothesis in 2010 part 2 (1)
- Cholesterol JUPITER link (1)
- Cholesterol Milano style (1)
- Cholesterol pacitimbe and ACAT (1)
- Cholesterol presentation: Between countries (1)
- Cholesterol ratios through the looking glass (1)
- Cholesterol ratios: Torcetrapib again (1)
- Cholesterol reflectivity at 400nm (1)
- Cholesterol within nations studies (1)
- Cholesterol; it's not a competition (1)
- Cholesterol; MESA and EBCT (1)
- Cholesterol; statins kill? (1)
- Cholesterol: ASTEROID destroys lipid hypothesis (1)
- Cholesterol: Do chylomicrons clog your arteries? (1)
- Cholesterol: Do chylomicrons clog your arteries? (2) (1)
- Cholesterol: LCAT and rabbits (1)
- Cholesterol: LDL in Oslo (1)
- Cholesterol: More epidemiology (1)
- Cholesterol: Near miss in Edinburgh (1)
- Cholesterol: Peto seeing some light? (1)
- Cholesterol: statins and oxLDL (1)
- Choose your insulin sensitivity well (1)
- Cirrhosis and corn oil (1)
- Cirrhosis and fish oil (1)
- Cirrhosis and fructose (1)
- Clofibrate and PUFA (1)
- Coconut oil and obesity (1)
- Coconuts and Cornstarch in the Arctic? (1)
- Coffee (1)
- Colorectal cancer and cholesterol (1)
- Colorectal cancer; fiber and the PPT (1)
- Complex I: Hoffer and B3 (1)
- Complex IV and control of delta psi (1)
- Conditioning Research on bad carbs (1)
- Confirmation Bias in my head (1)
- Confirmation bias is not just in my head (1)
- Confirmation bias is so nice (1)
- Coronary Artery Calcium Score and Scleroderma (1)
- Coronavirus is possibly everywhere (1)
- Costa del Glasgow (1)
- Covid playground (1)
- COVID-19 (1)
- CPT1aL479 resurfaces nicely (1)
- Crabtree and cardiovascular surgery (1)
- Credo (1)
- Cynthia Kenyon link (1)
- Dave Asprey and Dr Veech (1)
- David Blaine and refeeding syndrome (1)
- Dead people DO bleed... (1)
- Death by dogma (1)
- Delta psi and insulin and ROS (1)
- Delta psi and ROS (1)
- Denmark purchased using Flora profits? (1)
- Deuterium protected linoleic acid (1)
- DHA in rats (1)
- Diabetes and cardiac apotosis (1)
- Diabetes and hunger (1)
- Diabetes in Sweden (1)
- Diabetes in Sweden update (1)
- Diabetes; endothelial damage (1)
- Diabetic and hungry? (1)
- Diabetic nephropathy and the lost Swede (1)
- Diagnosing and Treating Vitamin B12 Deficiency Video (1)
- Do you believe in MRI scanners? (1)
- Dodgy D'Anci (1)
- Double Bond Index and longevity in humans (1)
- Dr Davis links (1)
- Dr Doug Wallace on mitochondria (1)
- Dr Ravnskov on statins for primary prevention of CVD (1)
- Dr Uffe Ravnskov MD PhD interview (1)
- Dr Wolfgang Lutz Obituary (1)
- Dunnigan Familial Partial Lipodystrophy (1)
- Earning a crust (1)
- Easiyo (1)
- Eat as much starch as you wish (1)
- Eating lots of meat and nothing much else (1)
- EBCT scan (1)
- EFA deficiencies? (1)
- Eggs are here (1)
- Eggs in Ontario (1)
- Electrochemistry (1)
- Electrochemistry (2) Superoxide (1)
- Electron Transport Chain image (1)
- Endocannabinoids in brain and adipocytes (1)
- Endotoxin Absorption on a High Fat Diet (1)
- Endurance and oxygen flux during fatty acid oxidation (1)
- Energy expenditure in obese vs slim non dieters (1)
- EPIC HbA1c and heart attacks (1)
- Essential fatty acids are essential (1)
- Excession (1)
- Faking it with selenium (1)
- Familial Hypercholesterolaemia (1)
- Familial Hypercholesterolaemia and glucose (1)
- Familial Hypercholesterolaemia and porcelain (1)
- Familial Hypercholesterolaemia Brown and Goldstein (1)
- Familial Hypercholesterolaemia heterozygous survival (1)
- Fancy some serology? (1)
- Fancy some serology? (2) (1)
- Fancy some serology? (3) In Japan (1)
- Fasting insulin and weight loss (1)
- Fasting insulin and weight loss and calories-in vs calories-out (1)
- Fasting insulin and weight loss on a water fast (1)
- Fat storage and retrieval (1)
- Fathead Supersize Me and Sweden (1)
- Fathead Supersize Me and Sweden (2) (1)
- Fats and absorbing endotoxin (1)
- Feeling experimental? (1)
- FFA vs 4-HNE for activating uncoupling (1)
- Fiaf (1) Who's fat is it anyway? (1)
- Fiaf (2) starving amidst plenty (1)
- Fiaf (3) where next? (1)
- Fiaf (4) memes and fat (1)
- Fiaf (5) Meme Watching (1)
- Fiber inulin and cancer (1)
- Fiber sucrose and ulcers (1)
- FIP vaccines etc (1)
- FIRKO mice (1)
- FIRKO-isation without all the hassle? (1)
- FIRKO-ise (1)
- First meat (1)
- Flow Mediated Dilation: What does it mean? (1)
- Foie Gras (1) Peroxisomes (1)
- Foie Gras (10) Liver (1)
- Foie Gras (11) Hepatocyte mitochondria (1)
- Foie Gras (2) Lard fed rats (1)
- Foie Gras (3) carbohydrate (1)
- Foie Gras (4) RER (1)
- Foie Gras (5) An aside on how to stay slim (1)
- Foie Gras (6) inflammatory mRNAs (1)
- Foie Gras (7) What do you mean by inflammation? (1)
- Foie Gras (8) Vaughan's macrophages (1)
- Foie gras (9) Adipocyte ROS (1)
- Foie gras from safflower oil hiatus (1)
- Folate and homocysteine (1)
- Follow on to Tucker's post on PUFA in rats (1)
- Food fermented cream (1)
- Food; carnitas (1)
- Food; chicken salsa (1)
- Food; Mutton followed by cheesecake (1)
- Food; sausages (1)
- Food; steak and kidney casserole (1)
- Food: African Beef Stew (1)
- Food: Burgers (1)
- Food: Lardo; the real thing (1)
- Food: Liver and bacon (1)
- Food: Liver; can you over do it? (1)
- Food: Mutton or lamb in orange sauce (1)
- Food: Offal (1)
- Food: Optimal ice cream (1)
- Food: Pork in green salsa and random dessert (1)
- Food: Recipe group (1)
- Food: steak and kidney casserole (1)
- French paradox in Sweden (1)
- From Yeasts to Chloroquine (1)
- Fructose (01) There's a signal (1)
- Fructose (02) Obesogen (1)
- Fructose (03) NOX vs RET (1)
- Fructose (04) Normal Adults (1)
- Fructose (05) Four out of five diabetics (1)
- Fructose (06) Acipimox tangent (1)
- Fructose (07) Acipimox tangent II (1)
- Fructose (08) Acipimox and FFAs (1)
- Fructose (09) The Surwit hepatocyte (1)
- Fructose (10) A can of cola (1)
- Fructose and gout (1) (1)
- Fructose and gout (2) (1)
- Fructose and heart attacks (1)
- Fructose and lactic acid in Naked Mole Rats (1)
- Fructose and leptin (1)
- Fructose and lipolysis (1)
- Fructose and metabolic syndrome: Uric acid (1)
- Fructose and triglycerides (1)
- Fructose Glucose and Cholesterol (1)
- Fruit and vegetables (1) cause DNA damage (1)
- Fruit and vegetables (1) re post (1)
- Fruit and vegetables (10) WHI and cancer (1)
- Fruit and vegetables (11) link (1)
- Fruit and vegetables (12) WHEL and CVD (1)
- Fruit and vegetables (13) become eggs (1)
- Fruit and vegetables (14) Listeriosis is no fun (1)
- Fruit and vegetables (2) damage your DNA... latest study headline (1)
- Fruit and vegetables (3) last post (almost) (1)
- Fruit and vegetables (4) The asterisk (1)
- Fruit and vegetables (5) in Holland (1)
- Fruit and vegetables (6) WHEL study (1)
- Fruit and Vegetables (7) Mediterranean France (1)
- Fruit and vegetables (8) WHEL study and McDougall (1)
- Fruit and vegetables (9) potato fruits (1)
- Fruit Flies and NDI1 (1)
- FSA apple (1)
- FSA in Glasgow (1)
- Full blown linoleic acid deficiency: speculation (1)
- Getting fat (1) staying fat (1)
- Getting fat (2) staying fat; follow on (1)
- Getting fat (3) is good (1)
- Getting fat (4) is bad when you stop (1)
- Getting fat (5) Hunger (1)
- Getting fat is good (6) Official (1)
- GLP-1 agonists (1)
- Glucosamine and aged mice (1)
- Glucose as a cure for hypertriglyceridaemia? (1)
- Glucose from fatty acids: RQ of 0.454 (1)
- Glucose lactate and cancer (1)
- Gluten and cardiomyopathy (1)
- Gluten and gall bladders (1)
- Gluten and NK cells (forget the antibodies) (1)
- Gluten and rheumatoid arthritis (1)
- Gluten and schizophrenia SPECT scan (1)
- Gluten ataxia (1)
- Gluten coeliac and multiple sclerosis (1)
- Gluten Dr Briffa link (1)
- Gluten links from Bloggeier (1)
- Gluten poppy pictures (1)
- Gluten-Congratulations: You have coeliac disease (1)
- Gluten; thyroid and auto immunity (1)
- Gluten: Does coeliac disease require an infection? (1)
- Gluten: Not your average plant toxin? (1)
- Gluten: The NICE guidelines for UK diagnosis (1)
- Glycaemic load and breast cancer (1)
- Gourmand Rats? (1)
- Great Barrington Declaration (1)
- Great Barrington Declaration (2) (1)
- Green Tea Extract; superb antioxidant? (1)
- GSD IIIa ketones MAD and Veech again (1)
- GSD type I vs GSD type III: Cornstarch vs ketones (1)
- Guddling in the dark (1)
- Guddling in the dark for a respiratory quotient (2) (1)
- Guess the weight of the mouse competition (1)
- Gwyneth Paltrow has osteopaenia (1)
- Hall and CICO again (1)
- Hall and CICO part 2 (1)
- Hall and CICO part 3 (1)
- Have you thought about electron transporting flavoprotein dehydrogenase and its substrate electron transporting flavoprotein? (1)
- Hazel eats butter (1)
- HbA1c and Familial Hypercholesterolaemia (1)
- HbA1c: Crack vs smack for a lower reading? (1)
- HbA1c: Low glucose and acid (palmitic) (1)
- Heart failure and insulin resistance (1)
- Helicobacter and glucose (1)
- Helicobacter and hydrogen (1)
- Hepatic extraction of fructose (1)
- Hepatic insulin resistance (1)
- Hepatic insulin resistance in KD fed mice (1)
- Hepatic insulin resistance through caloric overload (1)
- Here we go in to Lockdown 2 (1)
- Heroin and IBS (1)
- High fat diet and fertility (1)
- High fat diets make you fat and stupid (1) (1)
- High fat diets make you fat and stupid (2) (1)
- High fat Dutch style (1)
- High fat fed mice on stearic acid (1)
- High fat meal is analgesic (1)
- HLA-B27 and Ebringer (1)
- HLA-B27 and Ebringer BSE text (1)
- HLA-B27 and Ebringer speech text (1)
- HLA-B27 some more (1)
- Holiday reading (1)
- How can insulin resistance cause weight gain? (1) ALDH2 (1)
- How can insulin resistance cause weight gain? (2) 0.1 μM (1)
- How can insulin resistance cause weight gain? (3) AD-9308 (1)
- How can insulin resistance cause weight gain? (4) amplification (1)
- How can insulin resistance cause weight gain? (5) MCTs (1)
- How incomplete was LUCA? (1)
- HOW MANY bananas a day? (1)
- How many eggs per day? (1)
- How much linoleic acid to get fat and insulin resistant? (1)
- How toxic is wheat? (1)
- How's it going (1)
- Hunting gathering and starving (1)
- Hyperglycaemia and free radicals (1)
- Hyperglycaemia is bad (1)
- Hyperlipid Protons ambassadors (1)
- I'm back (1)
- If there were time... (1)
- IgG IgA and sniffing a virus (1)
- IgG IgA and sniffing a virus which stinks (1)
- IHD and ghee (1)
- IHD single vessel disease (1)
- IHD Tracking plaque 1950s style (1)
- Impaired glucose tolerance in low-carbohydrate diet: maybe only a physiological state (1)
- In the gym (1)
- Inhibiting lipolysis using acipimox (1)
- Insulin and confusion (1)
- Insulin and the Rewards of overfeeding (1)
- Insulin detemir (1) (1)
- Insulin detemir (2) (1)
- Insulin detemir (3) (1)
- Insulin glucagon and protein (1)
- Insulin in the brain: Hyperphagia? (1)
- Insulin in the brain: off topic giggle (1)
- Insulin increases coupling in mitochondria (1)
- Insulin makes you hungry (1) (1)
- Insulin makes you hungry (10) Processing (1)
- Insulin makes you hungry (2) even in the presence of hyperglycaemia (1)
- Insulin makes you hungry (3) a matter of semantics and free fatty acids (1)
- Insulin makes you hungry (4) unless you keep it out of your brain (1)
- Insulin makes you hungry (5) except when you resist (1)
- Insulin makes you hungry (6) except when you snort it (1)
- Insulin makes you hungry (7) superoxide is satiety (1)
- Insulin makes you hungry (8) Blokes (1)
- Insulin makes you hungry (9) Women (1)
- Insulin mimesis and NOX enzymes (1) A principle (1)
- Insulin mimesis and NOX enzymes (2) Lactate (1)
- Insulin mimesis and NOX enzymes (3) MCT (1)
- Insulin mimesis without NOX enzymes (4) MCT (1)
- Insulin mimesis without NOX enzymes (5) MCT plus linoleic acid (1)
- Insulin mimesis without NOX enzymes (6) MCT versus linoleic acid (1)
- Insulin sensitivity makes you fat (1)
- Insulin sensitivity makes you fat: growth hormone receptor deletion (1)
- Insulin sensitivity makes you fat. Insulin resistance makes you fat. Discuss. (1)
- Insulin sensitivity makes you fat. Insulin resistance makes you fat. Discuss. (02) (1)
- Insulin sensitivity makes you fat. Insulin resistance makes you fat. Discuss. (03) Visceral vs subcutaneous (1)
- Insulin sensitivity makes you fat. Insulin resistance makes you fat. Discuss. (04) M scores (1)
- Insulin; the Un-dead and coffin nails (1)
- Insulin: Are you hungry? (1)
- Insulin: Are you hungry? Part 2 (1)
- Insulin: The Flatline Days (1)
- Intellectual honesty vs obfuscation (1)
- Interesting times on Mars (1)
- Intimal wall volume reductions with weight loss (1)
- Is the astrocyte-neuron lactate shuttle finished? (1)
- Is vaccine efficacy a statistical illusion? (1)
- It's never too late to normalise your glucose (so long as you are still alive) (1)
- Jan Kwasniewski comment (1)
- Japan and a Seven Countries Study follow on (1)
- Jay Bhattacharya in conversation with Lord Sumption (1)
- Jebb VS Nutt (1)
- Jimmy Moore on Dr Weil (1)
- John Hawks on Paleo in NY (1)
- Junk Food binge (1)
- Just a heads-up (1)
- Just a little on complex I and models (1)
- Just an announcement (1)
- Just an update (1)
- Kebabs (1)
- Ketoacidotic death in lactation! (1)
- Ketogenic Diet: Eat Food (1)
- Ketogenic diets are unhelpful and dangerous for managing mitochondrial diseases. Maybe (2) (1)
- Ketogenic diets are unhelpful and dangerous for managing mitochondrial diseases. Maybe. (1)
- Ketogenic vs moderate carbohydrate diets (1)
- Ketones for ALS? (1)
- Ketones in Tehran (1)
- Ketones without the side order of Danish Pastry please (1)
- Ketones: Should idiots be allowed to write the methods section of any "scientific" paper? (1)
- Ketosis and Protein (1)
- Ketosis links (1)
- Kitava: uric acid (1)
- Kwasniewski and cancer (1)
- Kwasniewski paper (1)
- Kwasniewski; praise the lard (1)
- Lactate as bulk energy transport (1)
- Lard makes hungry mice live longest (1)
- Latest obesity paradox (1)
- Let them eat fat: Ron Rosenbaum (1)
- Life (01) Random musings on carbon monoxide (1)
- Life (02) Polyprenyl derivatives at the origin of life (1)
- Life (03) ATP synthase (1)
- Life (04) On the bench top (1)
- Life (05) Why sodium ions? (1)
- Life (06) What's wrong with sodium ions? (1)
- Life (07) Two timelines (1)
- Life (08) Proto-Ech (1)
- Life (09) Ech (1)
- Life (10) Methyltransferase in methanogens (1)
- Life (11) Ferredoxin (1)
- Life (12) Loki and its membrane potential (1)
- Life (13) Skulachev in 1978 (1)
- Life (14) From Skulachev to LUCA (1)
- Life (15) Skulachev addendum (1)
- Life (16) Mulkidjanian: Na+ pump or Na+/H+ antiporter? (1)
- Life (17) Nick Lane on Proto-Ech (1)
- Life (18) Why stop at formaldehyde? (1)
- Life (19) Metallic iron and the origin of metabolism (1)
- Life (20) How primordial is oxidative phosphorylation? (1)
- Life (21) Pyrococcus furiosus (1)
- Life (22) FeNi hydrogenase (1)
- Life (23) Antiporting: Choose your ion well (1)
- Life (24) Porting over CCCP (1)
- Life (25) Left or right hand? (1)
- Life (26) MrpA MrpD NuoL NuoM and NuoN. Plus nt-Nha. (1)
- Life (27) Alphabet soup (1)
- Life (28) Proton Billiards (1)
- Life (29) Applied billiards to MRP and MBH (1)
- Life (30) Guesses about Na+ channels (1)
- Life (31) Chinese whispers (1)
- Life (32) On the correct side of the fence (1)
- Life (33) Transient hunger (1)
- Life (34) Complex I pumping (1)
- Life (35) NiFe pumping (1)
- Life (36) Complex I. Protons are large (1)
- Life (37) Just a gif of complex I (1)
- Life (38) Water Wires (1)
- Life (39) NuoH (1)
- Life (40) Proton pumping (1)
- Linoleic acid and Tuberous Sclerosis (1)
- Linoleic acid makes you hungry (1)
- Linoleic acid panel discussion (1)
- Lipid blockage (1)
- Lipoprotein(a) a prickly subject (1)
- Lipoprotein(a) and ascorbate (1)
- Lipoprotein(a) and DELTA (1)
- Lipoprotein(a) and genetics (1)
- Lipoprotein(a) and oxidised cholesterol (1)
- Lipoprotein(a) and oxidised lipids: What's your mimium requirement? (1)
- Lipoprotein(a) and the Fairies at the bottom of my garden (1)
- Lipoprotein(a) and tissue transglutaminase (1)
- Lipoprotein(a) Bantu recap (1)
- Lipoprotein(a) Bantu recap 2 (1)
- Lipoprotein(a) genetics press release (1)
- Lipoprotein(a) is oxidised (1)
- Lipoprotein(a) Oxford abstract (1)
- Lipoprotein(a); Bantu Lp(a) and Swedish Lp(a) (1)
- Lipoprotein(a): 7-ketocholesterol and cancer (1)
- LIRKO mice (1) (1)
- LIRKO mice (2) (1)
- LIRKO mice (3) The MCQ (1)
- live humans. They're just like mice! (1)
- Liver and insulin (not a cooking recipe...) (1)
- Liver and onions at 100 after Keep Fit (1)
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85 comments:
Regular commercial store-bought eggs. Yeah or nay?
"Yeah" if your diet is fast food
"Nay" if you already eat reasonable stuff like meat, potatoes, dairy etc.. and can afford to buy eggs from chickens that eat bugs and whatever they peck at on real ground
@GalicPudding
Re eggs - and chicken. What one buys at the store is a long way from what my grandmother raised on the farm.
I was on some small islands in the Caribbean about a decade ago - Anywhere that water pooled you would find chickens. They ate the lizards and plant growth. The eggs yokes looks starkly different and had the taste I remembered as a child.
The chicken meat as well was quite different - quite a treat.
The high corn feed they use with commercial chickens causes a very high level of LA - particularly in the skin. It is not really human food anymore.
Most of the 'free-range' chickens are not what people imagine. There is a list of words that I put in a group - organic, natural, free range, cage-free, lemon-scented, original-formula,
new-and-improved, sustainable, extra smooth, green, antioxidant. It is just advertising.
It is recently legal to raise chickens in the city (no roosters - why? We can have dogs barking - but no roosters crowing?). It is more work than one might assume - and what do you feed them in the winter? Not enough bugs.
Humans ate bugs (still do in some places) - my take is it was feast or famine - fasting - digging for grubs when starving - eating tubers and plants when the hunger was miserable. Life was brutal. That is what we evolved on. Quite a long way from the popular 'humming bird' diet so many are on.
Mean while, corruption keeps expanding. There is an evil tyranny of experts - a mix of big Ag, pharma, and bureaucrats that has decided on top down medical and health advice. Once one gets to the federal level, there is so much corruption that it is best to ignore anything they say. Not just health - every Fed level agency is rancid now - am I just a serf under some evil empire?
Break open a grocery store egg and a homegrown egg and compare them. There's a huge difference, at least in the US. The industrial eggs are pale and…diluted.
My understanding is that commercial eggs have a higher PUFA content also.
I'm lucky to live in a rural area and had my own chickens, until stymied by foxes, so now I buy eggs from a neighbor, whose hens are often outstanding in their field. When forced to buy grocery store eggs I go to the health food co-op and get ones that are purported to be "free range". Not anywhere as good as homegrown but still better than industrial.
I do miss having my own chickens. They're so entertainingly interactive.
Forgot to mention, again mostly in the US, industrially-raised animals, including chickens, live in horribly inhumane conditions. I refuse to support that.
There's one organic farm near our town that have a mobile hen house, basically a hen house built on a trailer. They move it around their meadows about once a week and of course lock the doors at night and collect the eggs. Those eggs are good but not noticably different from other certified organic eggs from supermarkets. Non-organic eggs have a different taste, texture and color. The yolks are a brighter, more organge yellow, I suspect they put something in the chicken feed to achieve this.
Chicken are interesting creatures to watch. My daughter keeps quail which are related. Each has its own character.
Peter, and others, have informed me about the dangers of Omega 6, particularly in high quantities in heavily oxidised and contaminated seed oils.
I remain curious why various commentators, of varying pedigrees, give a free pass to foods such as peanut butter made from roasted peanuts which presumably have high concentration of Omega 6 with the roasting presumably oxidising it.
I quite like it although it has tendencies of addiction. The dose makes the poison as Tucker often says, however what is a toxic dose of Omega 6 all of which is to varying degrees oxidised?
People seem to lose their mind when it comes to nuts. Walnuts for example which may only be edible when freshly harvested.
I am tending towards a typical diet enjoyed by "middle-class" !!!??? europeans a few centuries ago when O6 was low, presumably peanut butter was not a big seller, although the varieties of fruit and vegetables are not available anymore.
A default behaviour could be just to avoid all sources of O6 and go carnivore with possibly selected vegetables.
Garis: "A default behaviour could be just to avoid all sources of O6 and go carnivore with possibly selected vegetables."
That's mostly what I do. The only nuts are a few Brazil nuts every few days for the selenium. Nuts are way too easy to overdose on, especially if roasted and salted.
Peanuts, of course, are not a nut but a legume. I don't eat legumes either.
I suppose nuts that have not gone rancid are better than vegetable oils because they have not oxydized. But I still feel uneasy about eating a handful or two of nuts (walnut, hazelnut, cashes, Brazil).
Taking almonds as an example, as CN said it's hard to stop at a handful. But maybe this is a possibility because of industrialised foodtech? You can buy a 250g bag of shelled almonds for peanuts, pun intended which could last a little while subject to temptation. But if you were to eat (almond) oil based mayonnaise you could easily consume 100ml of the oil which would
have come from approx 160g of almonds, two thirds of that bag in a few gulps. Other oil sources have similar ratios of source to product.
(Incontinent nostalgia warning!)
We all had our own almond trees when I was growing up and I remember the trouble of harvesting them before the birds-rats-mice-neighbours did, then drying them in the sun and then hand shelling them. Mostly they would only be eaten in small quantities as a treat over the year. They weren't pasteurised either as all almonds must be now to prevent the harm caused by a lack of quality control possible in such vast quantities of almonds. I think the pasteurisation starts the breakdown of the oil and it's all downhill after that.
Btw the 'fruit' of the almond is that thinner greenish outer layer which covers the 'shell', perfectly edible in domestic varieties.
Peanuts, ugggh.
https://www.nytimes.com/2022/03/17/opinion/china-russia-xi-jin-ping.html
From as much as I could read before the paywall curtain descended --- what an appalling piece of garbage. One gets a good idea of the sort of raging propaganda our parents (grandparents? siblings?) grew up with in the 1930s and 40s. When the information channels are shut down and so tightly controlled as they are now we are probably even more restricted from discovering any clues about what is actually going on.
I was a short wave listener when I was a teen during the height of the previous anti-communist phobias and I sometimes tuned across Chinese etc radio stations which were jammed with characteristic squeals or low heterodynes. To protect us I assume. This is similar but worse.
Here Ya go:
"the BBC has chosen to revive shortwave radio broadcasts in an effort to keep its reporting available to a country that desperately needs it.
“It’s often said truth is the first casualty of war,” BBC Director-General Tim Davie said in a statement. “In a conflict where disinformation and propaganda is rife, there is a clear need for factual and independent news people can trust—and in a significant development, millions more Russians are turning to the BBC.”"
Now what you do is put that in a suitable logical framework:
{! “It’s often said truth is the first casualty of war,” BBC Director-General Tim Davie said in a statement. “In a conflict where disinformation and propaganda is rife, there is a clear need for factual and independent news people can trust—and in a significant development, millions more Russians are turning to the BBC.” }
And consider how that sort of reads the same when it is completely negated.
Apologies for posting this politics bumff here, I will delete later. I also want to express gratitude to Peter for being such a gracious blog-host.
I really got a chuckle out of Russell Brand's latest diatribe where he smashes some of the contradictions into each other at high speed.
https://youtu.be/NiRXysVrJ-s
You can buy Azov battalion coffee mugs on Amazon ?!?!!?
Pass—not that you might want to apply it to propaganda, but there's this: https://12ft.io
I couldn't make it through the whole Krugman article. China's vaccine is "home-grown"? Define that, please. People are making it in their kitchen?
Also, mRNA vaccines are effective against omicron? Obviously I've been looking at the wrong numbers. Or they've re-defined "effective" along with so many other words.
Pass, was that a reaction to the Krugman - China article? By the way, if you run out of free articles, try incognito mode, a different browser or a different computer of phone.
I didn't think it was all that bad. He points out the obvious, that the policy of draconian lockdowns didn't help because the population has not built natural immunity through exposure. That they insisted on locally developed traditional vaccines and delayed certification of mRNA may have added to their trouble or not. He shouldn't have presented that as a fact.
Cave, last I looked earlier this week, mRNA vaccines remain roughly 50% effective against symptomatic Omicron infection - in the US and Germany, but not in the UK. Never figured out whether someone is cooking the numbers or there is a simpler explanation.
"Never figured out whether someone is cooking the numbers or there is a simpler explanation."
Cooking the numbers is the simpler explanation.
And Occam's Razor applies.
Oh, and Eric, right on cue:
https://boriquagato.substack.com/p/cdc-reports-of-historical-covid-deaths?s=r
Pass, nothing controversial in Russel Brand's diatribe that I could see. Meta does seem to have flexible standards! BTW failed to work out how to negate a Logical Framework Approach...
cave, have you looked at Israel's all-cause mortality for the population, not just the elderly, through the omicron wave? Highest for (at least) the last 4 years via Euromomo. Worse than the Wuhan and Delta waves. My take is the Omicron head cold plus ADE from the vaccines, especially at 4 doses, is badness.
Eric, I still doubt the mRNA vaccines do any good but the track record of traditional coronavirus vaccines has always been a train wreck. That's why we don't have any traditional vaccines against ordinary coronavirus colds, which can be lethal in the elderly.
Bob, I suspect Jacinda Arden has a very, very tight definition for a coronavirus death in New Zealand currently...
Peter
"how to negate a Logical Framework Approach.."
I was thinking that when someone starts with " truth is the first casualty " etc that the first thing you should do is take them at their literal word and accept that everything they're saying is a lie. And then follow on like that to the rest of their statement.
Eric, the NYT is simply not my cup of tea.
Guess who is catching up?
https://www.health.harvard.edu/heart-health/saturated-fat-eaten-in-the-short-term-might-not-threaten-heart-health?utm_source=delivra&utm_medium=email&utm_campaign=WR20220318-Concentration&utm_id=3540437&dlv-emuid=426a5613-fc7f-4a0d-8372-7c8edd41e377&dlv-mlid=3540437
Monica, haha. The next question is how long it will take before they are solidly gaslighting us that they never even suggested saturated fat might be harmful for cardiac health...
Pass, I see what you mean. Your point went over my head because the fact that the BBC might be telling the truth about the situation in Ukraine (or anywhere) simply never ever crossed my mind. But, yes, it really is quite a funny statement about themselves and their reporting. Reminds me of the joke about the interview with Bojo:
"What's the best lie you have told since becoming Prime Minister?"
"I don't tell lies"
"Yes! That's my favourite too"
Peter
has anyone here read Trevor Marshall or Jim Stephenson Jr and their anti-vit D supplementation papers? Comments?
(but please not "I take it and...") Thanks
Eric and Peter – yes, I was paying attention to the Israeli numbers. Actually Israel and the UK were the ones I paid the most attention to, pretty much completely ignoring anything from the US as being unreliable.(Or perhaps more accurately, *more* unreliable.)
I've gotten heartily sick of numbers and charts and graphs, but the last time I looked closely at anything that purported to show vaccine efficacy*, it would typically only cover the first 4 to 6 months. Imagine that.
LA_Bob "Cooking the numbers is the simpler explanation." Perfect.
* I was mostly paying attention to the numbers of vaccinated and unvaccinated people being hospitalized or dying. Official calculations of "efficacy" are about as real-world useful as the relative risk numbers for taking statins to prevent heart attacks.
baggirl, I'm a complete vit D agnostic. The studies are all over the place and the only one of interest recently is D and covid, where I believe they used the activated, rapid onset form. It appears to work, which surprised me. Clinically I've not seen any great success with D supplementation (cats with low D and atopic dermatitis) and anecdote from clinicians trying in on cats for mycobacteriosis were not such that you would be tempted to use it as a therapy. Sadly.
I don't supplement but I do spend a huge amount of time in the sun once the UV is back, being lucky enough to have a garden allowing thorough sun exposure while working. The feeling of well being from the sun is my driver and, of course, paddling my canadian canoe for 4 hours down the Waveney in UV grade 8 is cool as an ability for a caucasian.
Peter
cave, yes, I too tend to follow things very carefully until I think I can make my mind up. Then I just follow a few key markers. Israel says the vaccine is a dud. New Zealand says attributing death to covid is a political act and the political peak will occur in about a week's time...
Peter
I have read a great deal about cholecalciferol, calcifediol & calcitriol over the past 10-15 years (and I do 'sun', UVB lamp & supplements+K2). I managed to read some hundreds of papers without coming across Marshall or Stephenson, but I guess I'll take a look. Dr David Grimes is always worth a read for a more general approach (http://www.drdavidgrimes.com/) but the 'bees knees'(pace Michael F Hollick & also the Vitamin D wiki https://vitamindwiki.com/) is Robin Whittle. Whittle is an electronic technician and computer programmer (so definitely up there with engineers & vets!) and his site (https://nutritionmatters.substack.com/), mostly about VitD, is truly excellent.
PS. Don't forget https://vdmeta.com/ - now up to 185 studies all D & Covid.
PPS. baggirl: Marshall's paper is behind a Wiley paywall. Johnson runs a pay-to-view website.. Consequently, it is difficult to comment.
@Eric
Effectifness of the vaccine?
The numbers out of Korea show a different story - hard to find the truth. Could be that the low number of infections in unvaccinated in Korea is due to prior exposure or not turning to the med system? But the numbers do call in question the claims made about the vaccine. I don't trust people that have repeatably lied to me - I am quite certain of one thing - it is not possible to know with any certainty the relative benefits/risks - all data has problems - but the vaccine data has a strong smell of fraud. When they tried to hide the data for 75 years it says something. The long term circulating spike - higher than in CoVid cases (Dr Been recently dived into it) - undertakers finding unusual clots in vaccine deaths - the lack of systematic autopsies all send off alarm bells for me.
One of the things I do is to test what is being reported vs what I learn fist hand. We have hosted international students - over 30 years - and I realized what they told me about what was happening in their country and what was in the news was almost never the same. I know 3 people that got SERIOUSLY sick from the vaccine - and 2 that died with (at 2 days and 5 days post vaccine). Seems unlikely that this is perfectly safe. I also can't 'calibrate' the risk I see in VARES - but there is clearly a signal - one that should have stopped the program IMO.
@Peter & Kevin FST
I've read EVERY vit-D paper I have been able to get my hands on - and lots of them are crap. Sick people don't go outside and thus would have lower vit-D. So it is the old arrow-of-causation problem. BUT - there are a few papers - RCT that show lower respiratory infection rates with children taking D3. There is no money in vit-D thus not much great research.
Re the https://vdmeta.com/ data - I tend to think the correlation is causative - due to the size of the effect. The papers showing failure of vit-D don't understand that it takes a long time to get the level up in someone with a low level (D3 is slowly converted in the liver). There was one paper(Spain) that used the active form of vit-D that appeared to work - but that paper was pulled due to non-consent(does not mean the science was wrong). But, if the grant money was focused on public health instead of subsidizing big Pharm, we would have definitive studies that are still lacking. (I think the lack of a proper vit-D study and ones on repurposed drugs is intentional)
There is another problem with vit-D papers. The low limit is set at 30 - where rickets appear, but tribes that live out doors similar to our evolutionary past average levels twice that. So most studies under-treat and see little or no effect is one possible explanation. My hunch is the optimal level is probably around 60. (wonder what cats that sit in the sun get?)
I think it is likely that evolutionary we started off dark skinned in the tropics and lost the pigment as we migrated north (actually, the genetic change happened more than once). I think it is likely that the lack of vit-D was the driver of this change. People that did not block the sun appear to have a survival benefit in Northern latitudes.
There is yet another problem - my initial deep dive into vit-D led me to the UV discovery in the 1920s - one would assume that afterwards there would be a systematic focus looking at other light frequencies and photo chemicals/health effects. Mostly a void. We do know that bilirubin appears to be reduced with yellow-green light and there is some effect of IR on the NO levels in the blood - also some more recent low quality work on LASER light - so the loss of pigment may have to do with other photo effects. Our understanding of light/EM radiation effects is primitive.
There is some low-level work showing effects of vit-D on immune system and calcium metabolism.
I do have some bias on this topic - I suffered from bad seasonal depression for much of my life - about 15 years ago, I was trying a light box - thought I was getting a small effect - never sure - an found a paper that compared depression scores between two groups - one treated with a giant gulp of D3 - the other the light box. The D3 worked much better - so I started taking 5,000IU/day and never stopped - I've never had the same serious depression again - my blood level stays around 60. I think it works for me - n=1 for what it is worth. I also don't get 2-week long colds like I used to - and have never had influenza again - n=1 - for what it is worth.
The intersection of the Ukraine war and PUFA. Not sure how to feel about this. Quote is from 3/19 Heather Cox Richardson.
"First, the war has affected not only Ukraine’s people and infrastructure, but also its ability to produce wheat, corn, and sunflower oil. Before the war, Ukraine was the world’s second biggest exporter of grains and biggest exporter of sunflower oil. It provided over half of the corn imports to the European Union, about a fifth of its soft wheat, and almost a quarter of its vegetable oil. (Soft wheat has less protein—gluten—than hard wheat, corn feeds Europe’s animals, and sunflower oil is in processed foods, including baby food, where it is hard to replace.)"
The fear mongering about shortages is in overdrive.. hard to worry about missing some type of food when others will be missing lives. I wouldn't believe anything you hear in the news.
I blame the USA and Russia for unleashing the horrors of war. As super powers with nukes - and the means to deliver them - why not fight on your own land? I live in the US and I don't see any good guys.
This has happened before in Vietnam - a proxy war - at the cost of a third country. Nobody wins in a war.
I think this conflict could have been avoided - and I fear it is happening so money flows for those pulling the strings.
This will be a huge problem. Supply of grain and PUFA oils will go down by a very significant percentage, and many just don't have the luxury of buying something else or living on grass-fed beef. It is easy to feel sufficiently insulated in Califoria, but in the end it is the world market price that will make itself felt.
Germany is a net exporter of wheat and timber, but what happened last year was that American and Chinese buyers bought directly from local producers at prices that drove up local prices significantly. Going into the equivalent of home depot last year, I was faced with empty shelves, and what was available was easily triple the usual price and of poor quality. The same thing will happen with food in the US, and it is going to be much much worse for low- and medium-income countries. Italy already fears a wave of refugees from Africa this summer because of famines. There are some that say Putin is hoping to drive refugees out of Ukrain and indirectly out of Africa to put pressure on the EU to in turn pressure Ukraine into concessions.
KevinFST: see https://www.trevormarshall.com/papers.htm no paywall there. Marshall's main point (at least to me) is that exogenous D3 binds the receptor and essentially renders it useless for it's immune function (http://autoimmunityresearch.org/transcripts/AR-Albert-VitD.pdf). Also, that D3 supps increase the storage D but not the active form, and all studies on D's effect need to viewed with this in mind. But yes, soooo many studies on the benefits of taking D it's hard to see the forest. It seems very reasonable that time in the sun has a multitude of yet unknown benefits, that D is just a marker. In my readings, there is also some static that Hollick has a lot to gain from pushing the message and selling his D supps.
https://www.nytimes.com/2022/03/23/health/covid-africa-deaths.html
So while there was considerable excess mortality (both counted as Covid and not) in South Africa and (just for comparison), also in India, there apparently wasn't in other countries such as Kenia or Serria Leone.
More Vitamin D because of latitude? Less funny industrial food?
After sifting through the comment section of the NYT article, a few things come up repeatedly:
- much of the population takes HCQ or other malaria drugs
- much younger population even than in SA or India
- less obesety
- and one very interesting comment (though I wouldn't agree that hypothiocyanite is a relative of chlorine bleach):
Jonathan D. Kaunitz, M.D.
UCLA School of Medicine
March 24
Populations in Western and Central Africa include cassava as a major source of calories. The African variant has a high content of the cyanogenic glycoside linamarin, which is converted to deadly hydrogen cyanide (HCN), requiring extensive preparation. HCN is detoxified to thiocyanate (SCN). Many of the West Africans populations suffer from forms of cyanide poisoning termed konzo. SCN is converted in the airway and salivary glands to the antiviral disinfectant OSCN (hypothiocyanite), a relative of household bleach (hypochlorite or OCl). We have hypothesized that ingestion of high amounts of cyanogens increases the concentrations of OSCN in the saliva and bronchial secretions, reducing the burden of virus, decreasing the infection rate: (Ingestion of Cyanogens from Cassava Generates Disinfectant Hypothiocyanite That May Decrease the Transmissibility of SARS-CoV-2 2021, Academia Letters DOI: 10.20935/AL1211). Further support of this hypothesis is in smokers, who are exposed to HCN in tobacco smoke and have high SCN levels. Although smokers with chronic lung disease have more severe COVID disease, smokers in general are less likely to become infected with COVID. There is indeed an inverse correlation between cassava ingestion and COVID death rate, explaining the low death rates in African cassava-consuming countries, especially Nigeria and the DRC.
Eric, a cabbage a day keeps the doctor away ...
Foods high in isothiocyanates include broccoli, watercress, daikon and many of the other cruciferae. One reason that cabbage white moths attack these plants is that they concentrate the isothiocyanate from the plant to make themselves repellant to predators, possibly even toxic. That's evolution hard at work!
(those foods are high in isothiocyanate precursors)
And this aspect of i.t.c. is interesting.
"Absorbed isothiocyanates are rapidly conjugated to glutathione in the liver, and then sequentially metabolized in the mercapturic acid pathway, before being excreted in the urine. "
https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/isothiocyanates
The downstream metabolite of paracetamol depletes glutathione so that neatly relates to what George H is saying here:
http://hopefulgeranium.blogspot.com/2022/03/is-acetaminophen-paracetamol-use-making.html?m=1
Hmm I'm not sure if that means that i.t.c. also depletes glutathione or that it enhances it? Probably the former. Maybe I'll stay off the cabbage for now, or not have broccoli with paracetamol ...
Only this past week have we officially reached the point in Germany where unvaccinated, double and triple vaccinated are all equally likely to test positive.
https://www.spiegel.de/wissenschaft/medizin/coronavirus-infizierte-genesene-tote-alle-live-daten-a-242d71d5-554b-47b6-969a-cd920e8821f1
Hearing from young and middle aged folk who caught it recently, it is mostly of the nasty cough, be off-work for two weeks varriety. Time for spring to kick in!
Having just run across this YouTube channel, I see another timehole in my future. My new favorite Internet medic, Dr. Glaucomflecken. For starters, two very short videos exposing the truth about CDC guidelines:
https://www.youtube.com/watch?v=FsFvnpcFGA4
https://www.youtube.com/watch?v=U5w_bLHhY18
I was rather surprised to see such a reasonable (by my lights) article in STAT News: "How we got herd immunity wrong". It even has nice things to say about the Great Barrington Declaration. https://www.statnews.com/2022/03/25/how-we-got-herd-immunity-wrong/
Then the comments. Aargh. Why don't people realize that a little courtesy and respect goes a long way? A tiresome digression about Sweden—I'm so past the point of believing numbers from almost anywhere that I don't see the usefulness of those debates. No one has yet addressed the actual point of the article, which is herd immunity.
cave, the whole debacle about herd immunity is an embarrassment to the medical profession. Especially the WHO shifting the definition to require vaccination to achieve this. Have these people never heard of the archives available of everything that is posted on tinternet? And their changing definition of a vaccine to accommodate the various clot-shots. Do these organisations think we are that stupid? Obviously yes, happily they're wrong about that too. My own feeling is that the WHO in particular has come out of this very, very badly. Like almost all other agencies and government health departments...
Peter
Peter, Cave, and all, Basically, I see the whole crappy bat-shit show as nothing but a medicinal Ponzi scheme. I'm still unjabbed. I get quite a bit of knee-jerk grief from Team-vaxx in my social circle, and some in my golf club are still trying to get me defenestrated (what a delightful word!). There is a lot of whispering that goes on. The multi-jabbed in the club are going down like flies, but no fatalities, or seemingly any serious knock-on issues as of yet, thankfully. Some are getting Covid for the 3rd time. I've read 100's of S2/C19 papers etc., etc., these last few years, and my only conclusion is to become a bigger sceptic than I ever was before. The WHO and GovCo have the dosh, and if it all is shown to have been a... mistake, they will just roll over and carry on as before. Just as Boris does. Folk seem to just shrug and kinda accept it.
Cap'n, regarding folks shrugging and accepting: this is why I've also been reading a lot of articles about the psychology of all this. Either I'm deluded or they are, and of course I prefer to believe they are.
This opinion piece in a recent BMJ is making the rounds. Some good comments too, including from Malcolm Kendrick. "The illusion of evidence based medicine" https://www.bmj.com/content/376/bmj.o702
"The advent of evidence based medicine was a paradigm shift intended to provide a solid scientific foundation for medicine. The validity of this new paradigm, however, depends on reliable data from clinical trials, most of which are conducted by the pharmaceutical industry and reported in the names of senior academics. The release into the public domain of previously confidential pharmaceutical industry documents has given the medical community valuable insight into the degree to which industry sponsored clinical trials are misrepresented. Until this problem is corrected, evidence based medicine will remain an illusion."
Meanwhile, I still can't manage to get infected. I only got the original Moderna shots. I wander freely around the local grocery store teeming with tourists, the auto parts stores and the laundromat, all maskless. I might have to re-open the idea of a South Dakota pub crawl…
Cave, Yep, I follow Malcolm, and a few other worthy Doc's here in Airstrip One, and some in the US as well. We could do with more like them! Robert Malone has a good article out on Substack on the same subject https://mail.google.com/mail/u/0/#search/evidenced/FMfcgzGmvfZXVNDzxzfpzNVSqgQmxNvh Meanwhile, there is this on Purdue Pharma.https://mail.google.com/mail/u/0/#search/evidenced/FMfcgzGmvfZXVNDzxzfpzNVSqgQmxNvh
Kinda depressing, but maybe a few chugalug's in South Dakota could be my cure, but I'd never get a visa! Ha, ha!!
Cap'n, your Google email links don't work for anybody else (says the annoyingly pedantic retired computer tech).
The Robert Malone article is where I got the BMJ link. It's at https://rwmalonemd.substack.com/p/the-illusion-of-evidence-based-medicine, for those who are interested.
Cave, Ah yes, slipped up again. It's reverting back to my gmail! Anyway, this is the other link on Purdue.https://disinformationchronicle.substack.com/p/when-a-unc-grad-student-confronted?token=eyJ1c2VyX2lkIjo0OTIyMzY2NiwiXyI6ImlJNy9aIiwiaWF0IjoxNjQ4NTg3NzgwLCJleHAiOjE2NDg1OTEzODAsImlzcyI6InB1Yi0yNjQyOTkiLCJzdWIiOiJwb3N0LXJlYWN0aW9uIn0.XUf9CjBY3EitMPpy8OTLJo2atZQ51cka2B70l3VYZUk&s=r
Cavenewt, it may be your cruel destiny to never catch this disease.
Have there been many cases of it in your area that you're aware of? I wonder about environmental sources of other organisms which could give some type of immunity to cv19. Like you I live in a rural/semi-rural area. Were surrounded by sheep and cows, flocks of parrots and other wild birds, possums, bit of a mouse surge from time to time, rabbits and so forth, and we live on rainwater which we collect from our roof. We ain't afraid of no bugs. Not much anyway. ( Knocks on wood, genuflects, reaches for garlic and holy water.) Oh, there are plenty of bats too.
Get yours today to be safe :)
https://m.theepochtimes.com/fifth-covid-19-vaccine-shot-may-be-needed-in-fall-fda-official_4370086.html
Peter, Let's not forget, SARS2 is a... syndrome. Is that BigPharma's end get-out?
"I SERIOUSLY expect that a series of new highly virulent and highly infectious SARS-CoV-2 (SC-2) variants will now rapidly and independently emerge in highly vaccinated countries all over the world and that they will soon spread at high pace. I expect the current pattern of repetitive infections and relatively mild disease in vaccinees to soon aggravate and be replaced by severe disease and death. Unfortunately, there is no way vaccinees can rely on assistance from their innate immune system to protect against coronaviruses as their relevant innate IgM antibodies are increasingly being outcompeted by infection-enhancing vaccinal Abs, which are continuously recalled due to the circulation of highly infectious Omicron variants. In contrast, Omicron’s high infectiousness would enable the non-vaccinated to train their innate immune defense against SC-2 while the infectious and pathogenic capacity of the new SC-2 variants would be debilitated in the non-vaccinated for lack of infection-enhancing Abs in their blood. Unless..."
- Geert Vanden Bossche
Full Bossche paper:- https://uploads-ssl.webflow.com/616004c52e87ed08692f5692/6244c3b09ad5701f3ec17765_GVB_s%2Banalysis%2Bof%2BC-19%2Bevolutionary%2Bdynamics.pdf
So, I'm averaging 30 eggs a day and trying to burn through some of them (scrambled) by feeding to my pyranese and karakachan guardian dogs. Anyone else do this, or know if anyone that does? Would love to hear Peter's thoughts on this.
I think you might be super-ovulating. Try not to get pregnant, at least not earlier today......
Peter
Remembering the recent discussion about eggs, and then Justin's mention today about his ovulation fecundity, cosmic propinquity requires a mention of this article I just ran across minutes ago. It is from 2015, and doesn't address PUFAs, but has some interesting facts about how eggs are produced.
"An Eggsperiment: Factory Eggs vs. Home-Grown Eggs"
https://healthbitesonline.blogspot.com/2015/07/an-eggsperiment-commercially-produced.html
Pass, I can only accept whatever cruelty fate delivers.
"Have there been many cases of it in your area that you're aware of? I wonder about environmental sources of other organisms which could give some type of immunity to cv19."
I've heard of a few people around here being infected. Probably because of our low population, but despite massive tourist influx, we got off pretty lightly in the last two years; the official dashboard reported only a handful of hospitalizations monthly. My barber had a pretty bad case recently and now is dealing with Bell's palsy; she was unvaccinated FWIW. I live in a rural area which, being desert, probably has less wildlife and insects than you. We do have bats which are fun to watch in the evenings. What type of immunity to COVID-19 might other organisms confer?
I ascribe my cruel fate mostly to the low carb lifestyle, based on my personal experience with URI's (none in 12 years) and anecdotal evidence from other low-carbers. That's not to say that's the only possible explanation, of course.
Having seen the Vanden Bosche post, the first paragraph provided more than enough depression, so I didn't feel compelled to read 40 pages more. Unless it provides hope for those of us who fell for the initial mRNA vaccination and now regret it. Oh, wait, maybe the vaccination is why I'm unable to catch the bug…
(Super-ovulating, hehehe!)
cavenewt, could it be that you actually had the bug and were one of the asymptomatic people?
Also, this discussion yielded 'defenestrated', 'fecundity' and 'propinquity'! I like you people :)
I struggle to seriously consider infornation when the source is so biased.
I've always had my own chooks for eggs and meat, but apart from the colour/texture I can't really tell the difference once they are cooked.
And even the texture difference is mostly due to freshness.
What I would like to know is the presence of contaminants in the eggs and in the meat of commercial chickens, and the nutritional values.
Also, the yellow fat in commercial chickens is due to colouring, and young pasture raised chickens aren't yellow at all.
That said, given the option I'd have pasture eggs, but since they cost 4 times the price of caged eggs, I can't really justify that money.
Lapis-exilis, that's a mean looking opossum you got there. Our possums appear to be much more innocent while still being just as annoying.
Cave: " What type of immunity to COVID-19 might other organisms confer?"
Somewhere in the vast outpourings of the talking heads I came across the observation that there is an epitope on the h1n1 (?) flu virus which resembles one on the CV19 spike protein. It might have been in the reports of the trial ( by ordeal) where healthy young volunteers were being exposed to various disgusting infectious substances related to CV19 the implication being that it could provide some degree of immunity. There are sure to be other coincidences like this. No-one has mentioned the idea recently that other corona viruses might provide some cross-immunity but it seems reasonable.
I also don't trust official statistics very much especially when comparing one country to another. Even do, while ~20% of the UK pop. currently have an active infection, the total cumulative figure of cv 'cases' from 2020 up till now is less than 33% of the total population viz 22.2 million cases versus pop of approx 67mill.
The disease has not yet run its full course but in many other countries less than 50% appear to have caught it. So maybe not everyone will.
If you've got bats then you've got plenty of insects! I like to sit outside with a bat detector on summer evenings. There are usually many more bats of different types flying around than you can see.
Lol!!!! That's what happens when my fingers move faster than my brain. That being said, I consider all farm related things an extension of me at this point. Hard not to after doing it in some sort of capacity for around 10 years now.
Ha! I thought it was an April first post!!!!! Now I see it was March 31st. Huge apologies, my bad!
Peter
Hi Sisifo,
The quality of our food is extremely hard to relate to outcomes. It's quite clear that carnivore using beef from USA industrial "farms" anecdotally produces impressive results (I guess from the people it works for!) How much better would fully or near-fully pastured animal derived food "work" is a hard question to answer. Not a simple study and subtle changes over decades might be needed.
But then 15 years ago people asked me if type of fat for a keto diet mattered and I had no data. Still don't really but Protons suggests non PUFA might be best nowadays... And even that has to be qualified.
Peter
Pass, I think the concept of other coronaviridae providing immunity was pooh poohed in the early days. It seems now quite validated nowadays but I didn't save the study. Also Federico Lois https://twitter.com/federicolois and his co worker suspect that a minimally virulent version of SARS 2 may have circulated through Auss/NZ etc before the Wuhan strain. Which is interesting as regards the lab leak of the engineered Wuhan strain as the primary source.
But overall, the concept of 100% susceptibility to a novel coronavirus has always seemed preposterous to me. People who pushed this should be removed from office and kept well away from Public Health for ever. Whitty and Fauci for a start.
Peter
Peter,
To clarify, I strongly believe that the quality of fat in the diet is paramount, I mostly eat grass fed beef and lamb, and occasionally kangaroo, deer and other game, I try to limit pork to a minimum and I mostly avoid chicken.
My point is, while we have analysis of fatty acid content for all those meats, and overall it's clear that grass fed beef and lamb have the least PUFAs, I haven't seen anything about eggs.
I've owned a few restaurants, I'm a chef and a pastry chef, and my taste buds are probably more used to recognize flavours than most people's, and yet I can't tell the difference from fresh cage eggs and fresh pasture eggs (including my own). This is what the article linked was about.
Now, in my opinion there is a huge difference between fresh eggs and not so fresh eggs, and if you believe that the eggs in a supermarket (cage or pasture) are fresh, you'd be disappointed.
But if the cage egg is as fresh as the pasture egg, there is no appreciable difference in flavour and texture.
So, I'm not saying that pasture eggs aren't better, I'm just saying that the article is biased and incorrect, and that I'd really love to see a fatty acids analysis between different kind of eggs.
Justin, are you feeding the eggs raw to your dogs? There is one enzyme in egg whites which is not supposed to be very healthful, avidin. It binds biotin but is mostly destroyed by cooking.
https://en.m.wikipedia.org/wiki/Avidin
OTOH egg yolks contain biotin so win/lose but maybe with large quantities of raw egg consumed the avidin could be a problem.
There's all sorts of other enzymes in there including lysozome (potent antibacterial). Since we live in the era of heavily processed food materials you can buy egg white lysosome by the truckload eg
https://www.kewpie.com/en/finechemical/egg/ew_lyso.html
Peter this is an earlier Italian paper with a similar observation ie a highly infectious non-virulent strain:
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02535-1
Virulent might have been the wrong word to use there, non-cytopathic would be better.
passthecream, haha! Opossums are cool! They have two wombs, little back paw thumbs, prehensile tails and 50 teeth!! (more than any other land animal in NA)! - and 13 nipples in a handy pocket. (Everything is better with pockets!)
And they are impervious to snake venom!
Get your opossum pet today! (Or irritate your friends
(They also deal with life's bumps by hissing and playing dead. Instead of something actually proactive and useful. Sometimes I think that God equipped them with every possible defense ever just to balance the unbelievable inability to handle it, lol!)
Peter - how can you say that??? Fauci is THE SCIENCE! I mean, you can't remove THE SCIENCE from office! Tsk-tsk!
This was an interesting read:
https://assets.ctfassets.net/9n3x4rtjlya6/2STUDp4PMD8v9vMmuha3PL/762c6266e7f21ad360aab7922f369ba0/Techies_in_Virusland_-_St_Petersburg__1_.pdf
Then there's the story of Covid being found in stored samples of Barcelona wastewater from 2019:
https://www.reuters.com/article/us-health-coronavirus-spain-science-idUSKBN23X2HQ
Could be the less virulent early version Peter mentioned (that I hadn't heard about). But I wonder what the chances of contamination by modern virus RNA are when one opens back samples during a pandemic.
People not knowingly getting infected seems to happen more often. Nobody in my or my wife's immediate family had it, and there's very elderly people, preschoolers, and teenagers in the lot. We are at best low carbish but make an effort to avoid PUFA, but with all the junk food our teenage kids are eating, they probably get a good dose of PUFA. Most of our relatives even cook with those good heart-healty oils. I was talking to an engineer in a company I visited this week, and she said it was the same thing in her family. Her daughters weren't getting it when half the class in daycare or primary school had it, and neither did her husband when just about everyone in his company was falling sick. Knock on wood...
Oh, the fortnight of unmoderated posting has run out again. Peter?
Pass, I scramble them. Thanks for the link though I knew about the biotin binder from something Chris Masterjohn might have written about a while back. That's why I always use raw egg yolks (less the white) in my post workout smoothie. I always figured there were antimicrobial components in the white. It only makes sense.
About eggs - i'm reading the Kwasniewski homo optimus book - (because Peter referred to him several times on the blog, and since i'm working through the blog back- to front and the name cropped up several times I got curious) and the man sounds ... How do I put it gently - like Alex Jones level off-his-rocker nuts while also making sense. He sure seems to think that egg yolks are the best source of protein. I don't know how that relates to modern day supermarket eggs - or why - but fwiw - there it is.
Weird book is weird.
Covid: my family all live in Israel, and it's still nuts there. As in, the police will monitor you via phone to make sure you follow quarantine rules. And the vaccine/boosters definitely seems to do absolutely zilch to prevent people from catching it. I personally keep thinking that it was a giant cash/power grab, and nothing more. but..... I'm one of these crazy anti-vaxxxx people who didn't take the jab, so what do i know. (sarcasm aside - i'm pro necessary vaccines. not this nonsense.)
Have a wonderful weekend everyone!
lapis,
"off-his-rocker nuts while also making sense". Apt. My concern re Dr K's approach is that it is not hypoinsulinaemic enough for the level of PUFA in the pork which it features heavily...
I worry a little about the Paleomedecina approach slightly on this front too, though they are more throughly ketogenic/hypoinsulinaemic in their approach so seem to be doing rather well.
Sarah Hallberg, Mary Enig and Kwasnieswki himself all suggest we don't have all of the answers. This is the case.
Peter
Hey Peter!
Isn’t he though? It’s half rock solid ideas and science with a solid dash of religious thinking…. At least it’s not boring!
I was wondering about the pork too - and I keep thinking - he was probably mostly familiar with European pork - which according to what Brad Marshall was saying was finished on barley and had a better lipid profile? Because he seems pretty adamantly against PUFAs…. I wonder if he knew the fat composition in pork/chicken in the USA and whether he’d still be recommending it?
Another thing I’m scratching my head over is the low-ish protein thing. My mum is an ex-surgeon turned Geriatric specialist in Israel, and sarcopenia seems like a horrible way to go about things. Isn’t higher protein intake protective, rather than damaging?(I’m nowhere near as smart as you or some of the commenters here, so I definitely have more questions than answers….) But then - if people like the ones you listed don’t have answers either - at least I’m in lovely company, tee hee ;)
Personally I am doing something with butter, egg yolks, cream and beef (and very dark chocolate and coffee because I’m an incurable junkie, haha!). I gain weight stupidly easy on ‘normal’ keto, and one day I just had to admit that if I have to walk around starving, raging and fat keto isn’t a panacea - and rediscovered this blog and fell down the rabbit hole. Why didn’t I read through your work back in 2008 when I first found it?! (Probably because it went over my head and I didn’t want to do any more homework. Sigh. Serves me right!)
Anyway. I definitely feel better and maybe even losing weight finally? If this works I’ll dance a merry jig. So sick and tired of having to fight this crap. 🙄 If it doesn’t I’ll just throw in the towel and do a Peterson. Le sigh.
Also - should add - if you, or any of the other lovely smart people on here have any advice/suggestions/thoughts on how to beat this obesity thing - I’m all ears.
Pass, Federico has made most of the points in the presentation on twitter. In six or seven tweet bites they're comprehensible (if you let him do the math). In bulk it's more than a bit overwhelming.
lapis, both Amber O'Hearn and Siobhan Huggins have much more experience of practicalities than I do. Their current personal approaches appear to be high fat, eaten first, and modest protein. @siobhan_huggins and @KetoCarnivore. Not as saturophilic as I.
Peter
Thank you Peter! I wasn't familiar with either of them - going to get my stalking on ;)
(I like Amber already - "Eat Meat. Not Too Little. Mostly Fat." I see the trolling and I like it 🤓)
I remember posting a video of Derick a while back and he has definitely picked up steam. Great nerd out session of him and Paul with a mention of the Petro interview!
Might be a good idea to include the link. Lol! Very comprehensive, so touches on a lot of different things.
https://youtu.be/oXWz4e6dfpM
Peter, you mentioned getting into the sun earlier. Out of interest, do you wear any kind of sunscreen, commercial or experimental?
Chris, nope.
Peter
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