Mike Eades forwarded this paper to me, by Dr Speijer:
Being right on Q: shaping eukaryotic evolution
How good is it?
He covers a vast field including loads on
The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency.
Supercomplex assembly determines electron flux in the mitochondrial electron transport chain
Mitochondrial fatty acid oxidation and oxidative stress: lack of reverse electron transfer-associated production of reactive oxygen species (another gift from Mike Eades).
I've far from finished reading the paper, these are just some of the gems. At some point I really will get round to a bit more on complex I and RET to regulate susbstrate processing but there is rather a lot happening at home and there might be something of a delay. To say the least.