Monday, September 28, 2020



Right. I've been back to the broken links issue and have noticed that, when you click on a link to a "search term" you get a blank Pubmed page. However in the URL of this broken link there is a complex set of gobbledygook but very close to the start is the PMID that the search term has previously pointed to. So in the post

the link to the paper by Wolever is broken. 

The URL above the blank Pubmed page from the link is this:

and 10889799 is the PMID. Pasting this in to the search box gets you to the paper originally linked to so

now gives access to the abstract as:

Dietary carbohydrates and insulin action in humans

After that it's a Sci-hub job.




Over the years I have slowly learned how not to blog.

For one thing, never use hyperlinks embedded as "here" or "these people".

Always cite the paper title, then anyone can copy paste this in to Duckduck or Pubmed and they can then side step the broken link when it goes down, as it will.

In the very early days I used the Pubmed search result URL as the hyperlink. This appears to have been fine for the last 15 years or so but recently Pubmed updated and all of those links have been lost. If a hyperlink from a simple word like "here" used to go to a search result URL it will be down and even I cannot always relocate the original paper.

Sometimes even if I know exactly which paper it was it's not always possible to find on on my sprawling hard drive.

You learn these things as you go along. Damn.



Dave Lull said...

I sometimes have luck searching for a defunct URL in the Internet Archive’s Wayback Machine and turning up a “snapshot” of the page it used to lead to:

vanwash said...

Excellent advice. What's that saying? Too soon we get old, too late we get smart...

Unknown said...

Hi Peter, I found the article about mice, and I thought of you! What do you think of this one, surely there has to be a different explanation for inflammation response: Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus:Implications for the Pathogenesis of Obesity
Mice and rats were fed either a standard rodent chow (CD) containing 4.0% (wt/wt) (g%) fat, a high-fat chow (HF) containing 36.0 g% fat from animal source, or an unsaturated fat-rich chow [oleic acid-rich (OL)] containing 36.0 g% fat from olive oil.

When pure saturated and unsaturated fatty acids were tested separately, there was a clear difference with greatest inflammatory effect produced by long-chain saturated fatty acids. Although some previous studies have evaluated the abilities of fatty acids to induce cytokine expression, this is the first time the phenomenon has been shown in the hypothalamus
But this is good, right? - Although food intake and body mass gain is the same, independently of the diet composition, the anorexigenic response to leptin is preserved in OL (olive oil) rats while completely blunted in HF rats.

Peter said...

Dave, there are too many to systematically fix...

vanwash, yes.

Hi Iryna

I think we might suggest that Velloso is extremely enthusiastic about Photoshop but has been appallingly bad at hiding this over the years. The paper you've found hasn't been retracted yet, give it time. Sometimes people are just, well... These are illustrative:

Mostly I assume all data are genuine and your job is merely to interpret it correctly. Occasionally you get misled. I'm loathe to waste time on this lab.


Wout Mertens said...

Hi Peter,

Can you show some examples of broken links? I want to see if I can find some way to automate fixing them.

I went back to 2012 but couldn't find broken links, perhaps PubMed fixed it? For example, works and redirects to

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